VIOLIN: Vaccine Investigation and Online Information Network

NS5
Gene Name	NS5
Sequence Strain (Species/Organism)	Japanese encephalitis virus
VO ID	VO_0011149
NCBI Protein GI	158702649
Other Database IDs	CDD:279336
Taxonomy ID	11072
Gene Strand (Orientation)	?
Protein Name	NS5
Protein pI	9.89
Protein Weight	8854.45
Protein Length	135
Protein Note	Flavivirus RNA-directed RNA polymerase; pfam00972
Protein Sequence	>ABW77689.1 NS5, partial [Japanese encephalitis virus] KREKKPGEFGKAKGSRAIWFMWLGARYLEFEALGFLNEDHWLSRENSGGGVEGSGVQKLGYILRDIAGKQ GGKMYAD
Molecule Role	Protective antigen
Molecule Role Annotation	Researchers constructed plasmid DNAs encoding JE virus proteins. Cytotoxic T lymphocytes (CTLs) were induced by NS5 in a mouse model. Three immunizations with pUJENS5 provided a 57% partial protection from a lethal dose of JE virus (Konishi et al., 2003).
Related Vaccines(s)	Japanese encephalitis virus DNA vaccine pUJENS5
References