VIOLIN: Vaccine Investigation and Online Information Network

NA
Gene Name	NA
Sequence Strain (Species/Organism)	Influenza A virus (A/chicken/Henan/12/2004(H5N1))
VO ID	VO_0011135
NCBI Protein GI	61698053
3D structure: PDB ID	2HTY
Other Database IDs	CDD:271235
Taxonomy ID	319102
Gene Strand (Orientation)	?
Protein Name	neuraminidase
Protein pI	6.62
Protein Weight	46889.862
Protein Length	535
Protein Note	Sialidase or neuraminidase (EC 3.2.1.18) of Influenza viruses A and B; cd15483
Protein Sequence	>AAX53527.1 neuraminidase [Influenza A virus (A/chicken/Henan/12/2004(H5N1))] MNPNQKIITIGSICMVIGIVSLMLQIGNMISIWVSHSIQTGNQHQAEPISNTNFLTEKAVASVTLAGNSS LCPISGWAVHSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPHRTLMS CPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESE CACVNGSCFTVMTDGPSNGQASYKIFKMEKGKVVKSVELEAPNYHYEECSCYPDAGEITCVCRDNWHGSN RPWVSFNQNLEYQIGYICSGVFGDNPRPNDGTGSCGPVSPNGAYGVKGFSFKYGNGVWIGRTKSTNSRSG FEMIWDPNGWTGTDSSFSVKQDIVAITDWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKESTIWTSG SSISFCGVNSDTVGWSWPDGAELPFTIDK
Molecule Role	Protective antigen
Molecule Role Annotation	Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with HA plasmid once and the NA plasmid twice survived 100% (Chen et al., 2009).
Related Vaccines(s)	Influenza virus DNA vaccine encoding NA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))
References