VIOLIN: Vaccine Investigation and Online Information Network

HA
Gene Name	HA
Sequence Strain (Species/Organism)	Influenza A virus (A/Indonesia/CDC594/2006(H5N1))
VO ID	VO_0011131
NCBI Protein GI	113495780
Other Database IDs	CDD:278910
Taxonomy ID	400810
Gene Strand (Orientation)	?
Protein Name	hemagglutinin
Protein pI	7.01
Protein Weight	62418.44
Protein Length	656
Protein Note	Haemagglutinin; pfam00509
Protein Sequence	>ABI36144.1 hemagglutinin [Influenza A virus (A/Indonesia/CDC594/2006(H5N1))] MEKIVLLLATVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRD CSVAGWLLGNPMCDEFINVPEWSYIVEKANPANGLCYPGNFNDYEELKHLLSRINHFEKLQIIPKSSWSD HEASLGVSSACPYLGRSSFFRNVVWLIKKNNTYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTRLYQNP TTYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNFIAPEYAYKIVKKGDSAI MKSELEYGDCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSPQRERRRKKRGLFG AIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLE RRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKC DNECMESIRNGTYNYPQYSEEARLKREEISGVKLESIGIYQILSIYSTVASSLALAIMMAGLSLWMCSNG SLQCRVCI
Molecule Role	Protective antigen
Molecule Role Annotation	Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC594/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 (Prabakaran et al., 2010).
Related Vaccines(s)	BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1))
References