VIOLIN: Vaccine Investigation and Online Information Network

HA
Gene Name	HA
Sequence Strain (Species/Organism)	Influenza B virus (Strain B/England/222/82)
VO ID	VO_0011117
NCBI Protein GI	122955
Other Database IDs	CDD:278910
Taxonomy ID	11527
Gene Strand (Orientation)	?
Protein Name	Hemagglutinin
Protein pI	8.36
Protein Weight	62677.29
Protein Length	761
Protein Note	{ECO:0000255\|HAMAP-Rule:MF_04072}.
Protein Sequence	>sp\|P10757.1\|HEMA_INBEN RecName: Full=Hemagglutinin; Contains: RecName: Full=Hemagglutinin HA1 chain; Contains: RecName: Full=Hemagglutinin HA2 chain; Flags: Precursor MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCP NCLNCTDLDVALARPKCMGTIPSAKASILHEVKPVTSGCFPIMHDRTKIRQLPNLLRGYENIKLSTRNVI NAERAPGGPYIIGTSGSCPNVTNGNGFFATMAWAVPKDNKTATNPLTVEVPYICTKGEDQITVWGFHSDN AIQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGV LLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKY RPPAKLLKERGFFGAIAGFLEGGWEGMIAGWHGYTSHGAHGVAVAADLKSTQEAINKITKNLNSLSELEV KNLQRLSGAMDELHNEILELDEKVDDLRADTISSQIELAVLLSNEGIINSEDEHLLALERKLKKMLGPSA VDIGNGCFETKHKCNQTCLDRIAAGTFNAGEFSLPTFDSLNITAASLNDDGLDNHTILLYYSTAASSLAV TLMIAIFIVYMVSRDNVSCSICL
Molecule Role	Protective antigen
Molecule Role Annotation	Immunization and challenge experiments in mice indicated that even though vaccination with the recombinant HA vaccinia viruses derived from Influenza B virus (Strain B/England/222/82) induced different levels of cross-reactive neutralizing antibodies, mice vaccinated with either recombinant vaccinia virus were protected from infection with either subpopulation of influenza virus (Rota et al., 1987).
Related Vaccines(s)	Recombinant vaccinia virus encoding HA from Influenza B virus (Strain B/England/222/82)
References

HA