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pepN

Gene Name pepN
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887403
NCBI Protein GI 57116994
Locus Tag Rv2467
Genbank Accession AL123456
Protein Accession YP_177885
Taxonomy ID 83332
Gene Starting Position 2768985
Gene Ending Position 2771570
Gene Strand (Orientation) +
Protein Name aminopeptidase PepN
Protein pI 4.68
Protein Weight 87835.24
Protein Length 861
Protein Note Also known as pepDLysyl aminopeptidase (LYS-AP) (alanine aminopeptidase)
DNA Sequence 
>NC_000962.3:2768985-2771570 Mycobacterium tuberculosis H37Rv, complete genome
CGTGGCCCTTCCAAACCTCACGCGGGACCAAGCCGTCGAACGCGCCGCCCTGATAACCGTGGACAGCTAC
CAGATCATTCTCGATGTGACCGACGGTAACGGCGCTCCCGGCGAACGCACCTTCCGGTCGACCACCACCG
TGGTGTTCGACGCACTCCCCGGCGCCGACACGGTCATCGACATCTCCGCCCACACCGTGCGCCGCGCCAG
CCTCAACGACCAAGACCTGGACGTCTCGGGATATGACGAGGCGGCCGGGATCCCGTTGCGCGGACTGGCC
CAGCGCAACGTCGTCGTCGTCGACGCCGACTGCCACTACTCCAATACCGGCGAGGGCCTGCATCGGTTTG
TCGATCCGGTGGACGGCGAGACCTACCTGTACTCGCAATTCGAAACCGCCGACGCCAAGCGCATGTTCGC
CTGCTTCGACCAACCCGACCTCAAGGCCACGTTTGACGTGCGGGTGACCGCGCCCGCGCACTGGAAGGTG
ATCTCCAACGGCGCGCCGCTGGCCGCGGCAAACGGCGTACACACCTTCGCCACTACCCCGCGGATGAGCA
CCTATCTGGTGGCCTTGATCGCCGGACCATACGCGGCCTGGACGGACACTTACATCGACGACCACGGGGA
AATCCCACTCGGCATCTATTGCCGGGCCTCGCTTGCCGAATACATGGACGCCGAGCGGCTGTTCACCCAA
ACCAAGCAGGGATTCGGCTTCTACCACAAGCACTTTGGCCTGCCATACGCGTTCGGCAAGTACGACCAGC
TCTTCGTCCCCGAATTCAACGCCGGCGCAATGGAAAACGCCGGCGCGGTGACCTTCTTGGAGGACTACGT
CTTCCGCAGCAAGGTCACCCGGGCATCCTATGAGCGGCGCGCGGAGACCGTGCTGCACGAGATGGCCCAC
ATGTGGTTCGGCGACCTGGTCACCATGACCTGGTGGGACGATCTGTGGCTGAACGAGTCCTTCGCCACCT
TCGCCTCGGTGCTGTGCCAAAGCGAGGCCACCGAATTCACCGAGGCTTGGACGACGTTTGCGACCGTGGA
GAAGTCTTGGGCGTATCGCCAAGACCAGCTGCCGTCGACGCACCCGATCGCCGCCGACATCCCCGACCTG
GCCGCTGTCGAGGTGAACTTCGACGGGATCACCTACGCCAAGGGCGCCTCGGTGCTCAAACAGCTCGTTG
CCTACGTCGGGCTGGAGCGCTTTCTGGCCGGCCTGCGTGACTACTTCCGCACGCACGCTTTTGGCAATGC
CAGCTTTGACGATCTGCTGGCCGCGTTGGAAAAGGCCTCGGGCCGCGACCTGTCGAATTGGGGCGAGCAG
TGGCTGAAGACGACCGGGCTCAACACCCTGCGACCAGATTTCGAGGTTGATGCCGAGGGCAGGTTCACCC
GGTTCGCGGTGACACAGAGCGGTGCGGCACCCGGCGCAGGTGAGACCAGGGTGCATCGGTTGGCGGTGGG
CATCTACGACGATGATGGTTCCAAGAGTTCCGGCAAGCTGGTCCGGGTGCACCGCGAGGAACTCGATGTC
TCCGGTCCGATCACGAACGTCCCTGCGCTGGTTGGCGTTTCGCGCGGGAAACTGATTCTGGTCAACGACG
ACGACCTGACCTACTGTTCGCTGCGGCTGGACGAGCGGTCGCTACAGACCGCGCTAGACCGCATCGCCGA
CATCGCCGAGCCGCTGCCGCGCACGCTGGTGTGGTCGGCCGCCTGGGAAATGACCCGTGAAGCCGAACTG
CGTGCCCGCGACTTCGTGTCACTGGTGTCCGGCGGCGTGCACGCAGAAACGGAGGTCGGGGTCGCGCAGC
GGCTGCTGCTACAGGCGCAGACAGCGTTGGGTTGCTATGCCGAGCCCGGCTGGGCCCGGGAGCGGGGATG
GCCGCAGTTCGCCGACCGGCTGCTGGAGTTGGCGCGCGAAGCCGAGCCTGGGTCGGATCATCAGCTGGCC
TATATCAACTCGCTGTGTTCGTCGGTGTTGTCCCCCCGGCATGTGCAGACCCTAGGGGCGTTGCTCGAGG
GTGAGCCCGCCGCATGTGGATTGGCAGGCTTAGCCGTCGACACCGACCTGCGCTGGCGGATCGTAACCGC
GCTGGCCACCGCGGGCGCCATCGACGCCGACGGGCCGGAGACACCGAGAATCGACGCCGAGGTGCAGCGC
GACCCGACTGCCGCCGGAAAGCGGCATGCCGCCCAGGCCCGCGCGGCGCGGCCACAGTTCGTCGTCAAGG
ACGAGGCATTCACCACGGTGGTCGAGGACGACACCCTGGCCAACGCCACTGGCCGCGCGATGATCGCCGG
CATTGCCGCACCCGGACAAGGCGAGCTGCTCAAGCCGTTCGCGCGACGCTACTTTCAGGCGATCCCCGGA
GTATGGGCACGGCGATCCAGCGAAGTCGCGCAATCGGTGGTGATTGGCCTGTATCCGCACTGGGACATCA
GCGAGCAGGGCATCACCGCCGCCGAGGAGTTCCTCAGCGACCCCGAGGTTCCGCCCGCATTGCGCCGGCT
GGTGCTCGAGGGCCAGGCCGCGGTGCAGCGATCGTTGCGGGCCCGCAACTTCGACGCTGACGGCTA
Protein Sequence 
>YP_177885.1 aminopeptidase PepN [Mycobacterium tuberculosis H37Rv]
MALPNLTRDQAVERAALITVDSYQIILDVTDGNGAPGERTFRSTTTVVFDALPGADTVIDISAHTVRRAS
LNDQDLDVSGYDEAAGIPLRGLAQRNVVVVDADCHYSNTGEGLHRFVDPVDGETYLYSQFETADAKRMFA
CFDQPDLKATFDVRVTAPAHWKVISNGAPLAAANGVHTFATTPRMSTYLVALIAGPYAAWTDTYIDDHGE
IPLGIYCRASLAEYMDAERLFTQTKQGFGFYHKHFGLPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYV
FRSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWDDLWLNESFATFASVLCQSEATEFTEAWTTFATVE
KSWAYRQDQLPSTHPIAADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLERFLAGLRDYFRTHAFGNA
SFDDLLAALEKASGRDLSNWGEQWLKTTGLNTLRPDFEVDAEGRFTRFAVTQSGAAPGAGETRVHRLAVG
IYDDDGSKSSGKLVRVHREELDVSGPITNVPALVGVSRGKLILVNDDDLTYCSLRLDERSLQTALDRIAD
IAEPLPRTLVWSAAWEMTREAELRARDFVSLVSGGVHAETEVGVAQRLLLQAQTALGCYAEPGWARERGW
PQFADRLLELAREAEPGSDHQLAYINSLCSSVLSPRHVQTLGALLEGEPAACGLAGLAVDTDLRWRIVTA
LATAGAIDADGPETPRIDAEVQRDPTAAGKRHAAQARAARPQFVVKDEAFTTVVEDDTLANATGRAMIAG
IAAPGQGELLKPFARRYFQAIPGVWARRSSEVAQSVVIGLYPHWDISEQGITAAEEFLSDPEVPPALRRL
VLEGQAAVQRSLRARNFDADG
Molecule Role Protective antigen
Molecule Role Annotation This protein has been used to prepare a fusion protein for TB vaccine development (Junqueira-Kipnis et al., 2022).
Related Vaccines(s) PEPf + Advax4
References