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N protein

Gene Name N protein
Sequence Strain (Species/Organism) 18537/Human orthopneumovirus
NCBI Protein GI BAA00637
Other Database IDs CDD:397378
Taxonomy ID 11250
Gene Strand (Orientation) ?
Protein Name N protein
Protein pI 7.12
Protein Weight 41228.94
Protein Length 391
Protein Note clones C9, G15, B53, E41, R4, F5, D35, C85, AA75, and 7N30;
subgroup B
Protein Annotation Protective antigen
Protein Sequence 
>BAA00637.1 N protein [Human orthopneumovirus]
MALSKVKLNDTLNKDQLLSSSKYTIQRSTGDNIDTPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYA
MSRLGREDTIKILKDAGYHVKANGVDITTYRQDINGKEMKFEVLTLSSLTSEIQVNIEIESRKSYKKLLK
EMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEIKRYKGLIPKDIANSFY
EVFEKHPHLIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGSGQVMLRWGVLAKSVKNIMLGHASVQAE
MEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAA
KAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKEDDVEL
Molecule Role Defense factor
Molecule Role Annotation (Oliveira et al., 2013)N protein interacts with viral RNA, generating a helicoidal nucleocapsid, responsible for genome and antigenome resistance to RNAse. RSV nucleoprotein (N) is essential for virus assembly and replication as part of the viral ribonucleoprotein (RNP) complex.
Related Vaccines(s) (rBCG-N-hRSV) Recombinant Mycobacterium bovis BCG vaccine , MVA - RSV
References