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G1

Gene Name G1
Sequence Strain (Species/Organism) Sin Nombre virus
VO ID VO_0011086
NCBI Protein GI 1113859
3D structure: PDB ID 2K9H
Other Database IDs CDD:279853
Taxonomy ID 1980491
Gene Strand (Orientation) ?
Protein Name envelope glycoprotein G1
Protein pI 5.59
Protein Weight 9420.59
Protein Length 169
Protein Note SNV
Protein Sequence
>AAC54579.1 envelope glycoprotein G1, partial [Sin Nombre orthohantavirus]
FLVVLTTATAGLTRNLYELKIECPHTVGLGQGYVTGSVETTPVLFSQVADLKIESSCNFDLHVPATTTQK
YNQVDWTKKSSTTENTNAGAS

Molecule Role Protective antigen
Molecule Role Annotation Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice. Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene also was protective (Bharadwaj et al., 2002).
Related Vaccines(s) Sin Nombre virus DNA vaccine encoding G1
References