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L protein

Gene Name L protein
NCBI Protein GI AYC76673
Other Database IDs CDD:395756
CDD:275046
Taxonomy ID 11250
Gene Strand (Orientation) ?
Protein Name L
Protein pI 8.89
Protein Weight 240331.02
Protein Length 2166
Protein Note Mononegavirales RNA dependent RNA polymerase; pfam00946
Protein Annotation (Tiong-Yip et al., 2014)L protein is a viral RNA-dependent RNA polymerase that contains multiple enzyme activities required for RSV replication.
Protein Sequence 
>AYC76673.1 L [Human orthopneumovirus]
MDPIINGSSANVYLTDSYLKGVISFSECNALGSYLFNGPYLKNDYTNLISRQSPLLEHMNLKKLTITQSL
ISRYHKGELKLEEPTYFQSLLMTYKSMSSSEQIATTNLLKKIIRRAIEISDVKVYAILNKLGLKEKDRVK
PNNNSGDENSVLTTIIKDDILSAVENNQSYTNSDKNYSVNQNINIKTTLLKKLMCSMQHPPSWLIHWFNL
YTKLNNILTQYRSNEVKSHGFILIDNQTLSGFQFILNQYGCIVYHKGLKRITTTTYNQFLTWKDISLSRL
NVCLITWISNCLNTLNKSLGLRCGFNNVVLSQLFLYGDCILKLFHNEGFYIIKEVEGFIMSLILNITEED
QFRKRFYNSMLNNITDAAIKAQKDLLSRVCHTLLDKTVSDNIINGKWIILLSKFLKLIKLAGDNNLNNLS
ELYFLFRIFGHPMVDERQAMDAVRVNCNETKFYLLSSLSTLRGAFIYRIIKGFVNTYNRWPTLRNAIVLP
LRWLNYYKLNTYPSLLEITGNDLIILSGLRFYREFHLPKKVDLEMIINDKAISPPKDLIWTSFPRNYMPS
HIQNYIEHEKLKFSESDRSRRVLEYYLRDNKFNECDLYNCVVNQSYLNNSNHVVSLTGKERELSVGRMFA
MQPGMFRQIQILAEKMIAENILQFFPESLTRYGDLELQKILELKAGISNKSNRYNDNYNNYISKCSIITD
LSKFNQAFRYETSCICSDVLDELHGVQSLFSWLHLTIPLVTIICTYRHAPPFIKDHVVNLNEVDEQSGLY
RYHMGGIEGWCQKLWTIEAISLLDLISLKGKFSITALINGDNQSIDISKPVRLIEGQTHAQADYLLALNS
LKLLYKEYAGIGHKLKGTETYISRDMQFMSKTIQHNGVYYPASIKKVLRVGPWINTILDDFKVSLESIGS
LTQELEYRGESLLCSLIFRNIWLYNQIALQLRNHALCNNKLYLDILKVLKHLKTFFNLDSIDTALSLYMN
LPMLFGGGDPNLLYRSFYRRTPDFLTEAIVHSVFVLSYYTGHDLQDKLQDLPDDRLNKFLTCVITFDKNP
NAEFVTLMRDPQALGSERQAKITSEINRLAVTEVLSIAPNKIFSKSAQHYTTTEIDLNDIMQNIEPTYPH
GLRVVYESLPFYKAEKIVNLISGTKSITNILEKTSAIDTTDINRATDMMRKNITLLIRILPLDCNKDKRE
LLSLENLSITELSKYVRERSWSLSNIVGVTSPSIMFTMDIKYTTSTIASGIIIEKYNVNGLTRGERGPTK
PWVGSSTQEKKTMPVYNRQVLTKKQRDQIDLLAKLDWVYASIDNKDEFMEELSTGTLGLSYEKAKKLFPQ
YLSVNYLHRLTVSSRPCEFPASIPAYRTTNYHFDTSPINHVLTEKYGDEDIDIVFQNCISFGLSLMSVVE
QFTNICPNRIILIPKLNEIHLMKPPIFTGDVDIIKLKQVIQKQHMFLPDKISLTQYVELFLSNKALKSGS
HINSNLILVHKMSDYFHNAYILSTNLAGHWILIIQLMKDSKGIFEKDWGEGYITDHMFINLNVFFNAYKT
YLLCFHRGYGKAKLECDMNTSDLLCVLELIDSSYWKSMSKVFLEQKVIKYIVNQDTSLHRIKGCHSFKLW
FLKRLNNAKFTVCPWVVNIDYHPTHMKAILSYIDLVRMGLINVDKLTIKNKNKFNDEFYTSNLFYISYNF
SDNTHLLTKQIRIANSELEDNYNKLYHPTPETLENISLIPVKSNNRNKPKFCISGNTESMMTSTFSNKMH
IKSSTVTTRFNYSRQDLYNLFPIVVIDRIIDHSGNTEKSNQLYTTTSHQTSLVRNSASLYCMLPWHHVNR
FNFVFSSTGCKISIEYILKDLKIKDPNCIAFIGEGAGNLLLRTVVELHPDIRYIYRSLKDCNDHSLPIEF
LRLYNGHINIDYGENLTIPATDATNNIHWSYLHIKFAEPISIFVCDAELPVTANWSKIIIEWSKHVRKCK
YCSSVNRCILIAKYHAQDDIDFKLDNITILKTYVCLGSKLKGSEVYLVLTIGPANILPVFDVVQNAKLIL
SRTKNFIMPKKIDKESIDANIKSLIPFLCYPITKNGIKISLSKLKSVVNGDILSYSIAGRNEVFSNKLIN
HKHMNILKWLDHVLNFRSAELNYNHLYMIESTYPYLSELLNSLTTNELKKLIKITGSVLYNLPNEQ
Molecule Role Protective antigen
References