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LpnA

Gene Name LpnA
Sequence Strain (Species/Organism) Francisella tularensis subsp. tularensis SCHU S4
VO ID VO_0011079
NCBI Gene ID 3191792
NCBI Protein GI 56708002
Locus Tag FTT_0901
Genbank Accession AJ749949
Protein Accession YP_169898
Taxonomy ID 177416
Gene Starting Position 909953
Gene Ending Position 910402
Gene Strand (Orientation) +
Protein Name lipoprotein
Protein pI 9.16
Protein Weight 14909.46
Protein Length 149
Protein Note Paralog to conserved hypothetical lipoprotein lpnB.
DNA Sequence
>NC_006570.2:909953-910402 Francisella tularensis subsp. tularensis SCHU S4 chromosome, complete genome
TATGAAAAAAATAATTGAGCTTAGTCTTTTATCTTTATCAATCGCAGGTTTAGCGAGCTGTTCTACTCTA
GGGTTAGGTGGCTCTGATGATGCAAAAGCTTCAGCTAAAGATACTGCTGCTGCTCAGACAGCTACTACTG
AGCAAGCTGCTGCTGTATCTAAGCCAACTGCAAAAGTAAGTTTAAATAAACTTGGTCAGGATAAAATAAA
AGCAACTGTATATACAACATACAATAATAACCCACAAGGAAGTGTAAGATTACAATGGCAGGCTCCAGAA
GGTTCTAAGTGCCATGATACAAGCTTCCCAATTACTAAGTATGCTGAGAAGAACGATAAAACTTGGGCAA
CTGTAACAGTTAAGCAAGGTAATAACTTCTGTAGCGGTAAGTGGACAGCTAATGTAGTTTATGACAAAGA
AGTAATCGCTTCTGATTCAATAAATATTTA

Protein Sequence
>YP_169898.1 lipoprotein [Francisella tularensis subsp. tularensis SCHU S4]
MKKIIELSLLSLSIAGLASCSTLGLGGSDDAKASAKDTAAAQTATTEQAAAVSKPTAKVSLNKLGQDKIK
ATVYTTYNNNPQGSVRLQWQAPEGSKCHDTSFPITKYAEKNDKTWATVTVKQGNNFCSGKWTANVVYDKE
VIASDSINI

Molecule Role Protective antigen
Molecule Role Annotation Anti-lpnA MAbs conferred significant, although not complete, protection of naïve C3H/HeN mice from lethal challenge with F. tularensis LVS when administered therapeutically (Savitt et al., 2009).
References