VIOLIN: Vaccine Investigation and Online Information Network

groEL
Gene Name	groEL
Sequence Strain (Species/Organism)	Francisella tularensis
VO ID	VO_0011075
NCBI Protein GI	282159959
Other Database IDs	CDD:234573 CDD:239460
Taxonomy ID	510831
Gene Strand (Orientation)	?
Protein Name	chaperonin GroEL
Protein pI	4.6
Protein Weight	53514.52
Protein Length	634
Protein Note	chaperonin GroEL; Reviewed; PRK00013
Protein Sequence	>ADA79350.1 chaperonin GroEL [Francisella tularensis subsp. tularensis NE061598] MAAKQVLFSDEARAKMLDGVNTLANAVKVTLGPKGRNVVLDKSFGTPTITKDGVSVAKEIELEDKFENMG AQIVKEVASKTADVAGDGTTTATVLAQALLTEGLKAVAAGMNPMDLKRGIDKATARLVEELKALSKPCSD PKSIEQVGTISANSDATVGKLIADAMAKVGKEGVITVEEGKGFEDELDVVEGMQFDRGYLSPYFATNQEN MTTDLENPYILIVDKKISNIRDLLPILEGVSKSGRALLIIAEDVESEALATLVVNNMRGVVKVCAVKAPG FGDRRKAMLEDIATLTGATFVSEDLSMKLEETNMEHLGTASRVQVTKDNTTIIDGAGEKEAIAKRINVIK ANIAEANSDYDREKLQERLAKLSGGVAVIKVGAVTEAEMKEKKDRVDDALHATRAAVEEGIVAGGGVALI RAQKALDGLTGENDDQNYGIALLRKAIEAPLRQIVSNAGGESSVVVNQVKANQGNYGYNAANDTYGDMVE MGILDPTKVTRSALQHAASIAGLMITTEAMIGEIKEAAPAMPMGGGMGGMPGMM
Molecule Role	Protective antigen
Molecule Role Annotation	Researchers have shown that mice that had been immunized with purified heat shock protein 60 (Hsp60, groEL) isolated from Francisella tularensis were protected against a subsequent challenge with some strains of the bacterium (Hartley et al., 2004).
Related Vaccines(s)	F. tularensis GroEL protein vaccine
References