VIOLIN: Vaccine Investigation and Online Information Network

copN
Gene Name	copN
Sequence Strain (Species/Organism)	Chlamydophila pneumoniae
VO ID	VO_0010884
NCBI Protein GI	33241669
Other Database IDs	CDD:274206
Taxonomy ID	182082
Gene Strand (Orientation)	?
Protein Name	CopN
Protein pI	4.72
Protein Weight	42139.89
Protein Length	458
Protein Note	type strain
Protein Sequence	>NP_876610.1 CopN [Chlamydophila pneumoniae TW-183] MAASGGTGGLGGTQGVNLAAVEAAAAKADAAEVVASQEGSEMNMIQQSQDLTNPAAATRTKKKEEKFQTL ESRKKGEAGKAEKKSESTEEKPDTDLADKYASGNSEISGQELRGLRDAIGDDASPEDILALVQEKIKDPA LQSTALDYLVQTTPPSQGKLKEALIQARNTHTEQFGRTAIGAKNILFASQEYADQLNVSPSGLRSLYLEV TGDTHTCDQLLSMLQDRYTYQDMAIVSSFLMKGMATELKRQGPYVPSAQLQVLMTETRNLQAVLTSYDYF ESRVPILLDSLKAEGIQTPSDLNFVKVAESYHKIINDKFPTASKVEREVRNLIGDDVDSVTGVLNLFFSA LRQTSSRLFSSADKRQQLGAMIANALDAVNINNEDYPKASDFPKPYPWS
Molecule Role	Protective antigen
Molecule Role Annotation	Results of this study showed that intranasal immunization of BALB/c mice with heat-aggregated CopN protein and an Escherichia coli heat-labile toxin (LT) induced a strong immune response. The immunization induced statistically significant protection against intranasal C. pneumoniae challenge, the level of which correlated with the magnitude of CopN-specific lymphocyte proliferation (Tammiruusu et al., 2007).
Related Vaccines(s)	C. pneumoniae CopN protein vaccine
References