VIOLIN: Vaccine Investigation and Online Information Network

tfbA
Gene Name	tfbA
Sequence Strain (Species/Organism)	Actinobacillus pleuropneumoniae
NCBI Protein GI	AAA21929
Other Database IDs	CDD:279621
Taxonomy ID	715
Protein Name	transferrin-binding protein
Protein pI	7.6
Protein Weight	56362.89
Protein Length	630
Protein Note	Transferrin binding protein-like solute binding protein; pfam01298
Protein Sequence	>AAA21929.1 transferrin-binding protein [Actinobacillus pleuropneumoniae] MHFKLNPYALAFTSLFLVACSGGKGSFDLEDVRPNKTTGVSKEEYKDVETAKKEKEQLGELMEPALGYVV KVPVSSFENKKVDISDIEVITNGNLDDVPYKANSSKYNYPDIKTKDSSLQYVRSGYVIDGEHSGSNEKGY VYYKGNSPAKELPVNQLLTYTGSWDFTSNANLNNEEGRPNYLNDDYYTKFIGKRVGLVSGDAKPAKHKYT SQFEVDFATKKMTGKLSDKEKTIYTVNADIRGNRFTGAATASDKNKGKGESYNFFSADSQSLEGGFYGPK AEEMAGKFVANDKSLFAVFSAKHNGSNVNTVRIIDASKIDLTNFSISELNNFGDASVLIIDGKKIKLAGS GFTNKHTIEINGKTMVAVACCSNLEYMKFGQLWQQAEGGKPENNSLFLQGERTATDKMPKGGNYKYIGTW DAQVSKENNWVATADDDRKAGYRTEFDVDFGNKNLSGKLFDKNGVNPVFTVDAKIDGNGFTGKAKTSDEG FALDSGSSRYENVKFNDVAVSGGFYGPTAAELGGQFHHKSENGSVGAVFGAKQQVKK
Molecule Role	Protective antigen
Molecule Role Annotation	Immunoblots of iron-restricted profiles detected PotD2, heme-binding protein A (HbpA), and capsule polysaccharide export protein (CpxD) as well as surface antigens TbpA, TbpB, and OmlA. These data identify OM proteins that demonstrate immunogenicity and upregulation under conditions mimicking infection.(Chung et al., 2012)
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