VIOLIN: Vaccine Investigation and Online Information Network

ureC
Gene Name	ureC
Sequence Strain (Species/Organism)	Actinobacillus pleuropneumoniae serovar 2
NCBI Protein GI	303253439
Other Database IDs	CDD:183894 CDD:30031
Taxonomy ID	754254
Gene Strand (Orientation)	?
Protein Name	urease subunit alpha
Protein Length	572
Protein Note	urease subunit alpha; Reviewed; PRK13207
Protein Sequence	>gi\|303253439\|ref\|ZP_07339581.1\| urease subunit alpha [Actinobacillus pleuropneumoniae serovar 2 str. 4226] MALIIPRSQYVATYGPTVGDKVRLGDTDLWATIEQDFLTKGDECKFGGGKSVRDGMAQSSTATRDNPNVL DFALTNVMIIDAKLGIIKADIGIRDGRIVGIGQAGNPDTMDNVTPNMIIGASTEVHNGAHLIATAGGIDT HIHWICPQQAQHAIENGITTMIGGGSGPADGTHATTCTPGKFNIERMFQACEALPVNIGFFGKGNCSMLE PLKEQVVAGALGLKIHEDWGATPAVIDAALKVADEMDVQVAIHTDTLNESGFLEDTMKAINGRVIHTFHT EGAGGGHAPDIIKAAMYPNVLPASTNPTRPFTVNTIDEHLDMLMVCHHLDKRVPEDVAFADSRIRPETIA AEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMKAQRGALGDEGNDNFRIKRYIAKYTINPAIAH GICQYVGSLEVGKLADIVLWKPQFFGVKPEFVMKKGFISFAKMGDPNASIPTPQPVFYRPMFGANAKANT ESAVYFVSQASVDANIKAQYGIQKETLAVKGCRDVGKKDLVHNNATPEITVDPERYEVRVDGEHITCEPA TKVPLAQRYFLF
Molecule Role	Virmugen
Molecule Role Annotation	Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application (Tonpitak et al., 2002).
Related Vaccines(s)	Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine
References