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FlaA from C. jejuni 81-176
Gene Name	FlaA from C. jejuni 81-176
Sequence Strain (Species/Organism)	Campylobacter jejuni subsp. jejuni 81-176
VO ID	VO_0011046
NCBI Gene ID	4682159
NCBI Protein GI	121612545
Locus Tag	CJJ81176_1339
Genbank Accession	AY102622
Protein Accession	YP_001000997
Taxonomy ID	354242
Gene Starting Position	1255199
Gene Ending Position	1256929
Gene Strand (Orientation)	-
Protein Name	flagellin
Protein pI	5.37
Protein Weight	56366.68
Protein Length	576
Protein Note	FlaA; structural flagella protein; in Helicobacter the flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions
DNA Sequence	>NC_008787.1:1255199-1256929 Campylobacter jejuni subsp. jejuni 81-176, complete genome ACTATTGTAATAATCTTAAAACATTTTGCTGACTAGAATTTGCTTGAGCCATTGCATAAGAACCACTTTG GGCTAAGATGTTAGCTTTAGAGTAGTTTGCACTCTCACTTGCAAAGTCTACATCTCTGATTTGCGATTCT GCTGCTTTAACATTAACTTGAGTTACAGTAATGTTATTTATAGTTGATGTAACTTGATTTTGTATAGAAC CAATATCTGCTCTGATTTGATCTAGATTTGTTATAGCAGTTTCTGCTATATCCATAACCGCCATTGCACC TTTAAGAGTGGTTACACCTGCAGTCTCATCAGTTGTATTAGCAGCAGTAGTTTTAAGGGCTGCAAATTGA GAATTTCCTGAGCCAGAAGAAAATCCTGAACCTGCTGAAACAACATAAGTATTGCTCATTGAAGCCGCAC TTGAAATAATTTGTATTCCTTGACTCAATCCAACAGATAAATTTTTACCACTACCCACAGAAAATCCTGA ACCTCTAGAAAATCCTGAACCTTGTGCACTCATAAATGCAGAAATTGAACTTACATTTTGAGTAAAAACA AATTTTCCACCACCTTTATAAGAATTAAATCCCATAGCATCGGCATTGGTTGCTGAAATTTGACCTTTTG ATTCTCTTAAAGACACTGAAGATTGAGAAATCATATCTGTTGTACCCATACCTATAGCACTAAGATTGGT TCCACTTATATTGATATCTCTACCATCATTTTTAACTAAAGATAATCGCCCATAGTTTTCTTTTTGATTT GCCAAAATACCAGAACCAACACCTATATCTCCAGTAATTTTAATACCCCTGCCATCAGCCGATGTAAGAA CAAGCTTGCCGTTTTCATCTTTAGAAGCTTGAACTCCTGTGGTATCTTTAACCGCATTGATAGCTGAAAT CAAAGAGCCGTTACCATCTCCGTCTTTGTATTCAATTTTTCCTATAGTTACTCCATTAATGGCAAATTCT TGAGAAGTAGTTCCTTCTTTTATAGCATAAACGCCAGTTGTTTTTACATCGTAAGTTGCGCGAACTCCTG TTTTATCAGCGCTTTTATTGATCTCTTCAGCCAAAGCTCCAAGTCCTGTTCCAACTGAAGTTGAAATCAC AACATTATCAAATTTAAAATCTTCTATACCATTGTAGTTTTTAATAGTAAGACCAACCACACCTGAAGTA AAACTTTGAGCACCGGTTTCAAATCTTGTAACACCGATTTTAGAAGATTGAGTAGCACCGATAGTTGCTT TCACAGTTTGGTTTGAACTTGCGCCGATTTGGAATTCTTGATTGGTAAAATTTCCACTTAAAAGTTGCTT ACCATTAAATGAAGTAGTATTTGCGATATTATCAAGCTCTTCCATTAATTTATTAATATCTGCTTGAAGC ATAGTTCTTGTTTTTAAACTTTGTCCATCTTGAGCTGCTTGAGTAGCTTTAGTCTTGATAGTATCAAGAA TTTTTAATTGCTCATCCATAGCTTTATCTGCGGTTTGTAAGATACCTAAAGCATCATTACCATTTGATAT AGCTTGACCTAAAGTATTTGCTTGAGATCTTAAGCTATCTGCTATCGCCATCCCTGAAGCATCATCTGCT GCTGAGTTAATTCTAAGACCTGAACTAAGTCTGCTTAAAGAAGCATCTAAACTTTTAGCATTAAGATCAG AGTTTGCTTTTGCATTCAATGCTGCAACATTTGTGTTAATACGAAATCCCA
Protein Sequence	>YP_001000997.1 flagellin [Campylobacter jejuni subsp. jejuni 81-176] MGFRINTNVAALNAKANSDLNAKSLDASLSRLSSGLRINSAADDASGMAIADSLRSQANTLGQAISNGND ALGILQTADKAMDEQLKILDTIKTKATQAAQDGQSLKTRTMLQADINKLMEELDNIANTTSFNGKQLLSG NFTNQEFQIGASSNQTVKATIGATQSSKIGVTRFETGAQSFTSGVVGLTIKNYNGIEDFKFDNVVISTSV GTGLGALAEEINKSADKTGVRATYDVKTTGVYAIKEGTTSQEFAINGVTIGKIEYKDGDGNGSLISAINA VKDTTGVQASKDENGKLVLTSADGRGIKITGDIGVGSGILANQKENYGRLSLVKNDGRDINISGTNLSAI GMGTTDMISQSSVSLRESKGQISATNADAMGFNSYKGGGKFVFTQNVSSISAFMSAQGSGFSRGSGFSVG SGKNLSVGLSQGIQIISSAASMSNTYVVSAGSGFSSGSGNSQFAALKTTAANTTDETAGVTTLKGAMAVM DIAETAITNLDQIRADIGSIQNQVTSTINNITVTQVNVKAAESQIRDVDFASESANYSKANILAQSGSYA MAQANSSQQNVLRLLQ
Molecule Role	Protective antigen
Molecule Role Annotation	Mice were immunized intranasally with two doses of 3 to 50 microgram of MBP-FlaA. The protective efficacies of a 50 microgram of MBP-FlaA plus LT(R192G) dose against disease symptoms and intestinal colonization were 81.1 and 84%, respectively. When mice which had been immunized with 50 microgram of MBP-FlaA plus LT(R192G) intranasally were challenged orally with 8 x 10(10), 8 x 10(9), or 8 x 10(8) cells of strain 81-176, the protective efficacies against intestinal colonization at 7 days postinfection were 71.4, 71.4, and 100%, respectively (Lee et al., 1999).
Related Vaccines(s)	C. jejuni MBP-FlaA protein vaccine
References

FlaA from C. jejuni 81-176