VIOLIN: Vaccine Investigation and Online Information Network

cadF
Gene Name	cadF
Sequence Strain (Species/Organism)	Campylobacter jejuni
VO ID	VO_0011044
NCBI Protein GI	WP_002851185
Other Database IDs	CDD:275358 CDD:225439 CDD:143586
Taxonomy ID	194
Gene Strand (Orientation)	?
Protein Name	fibronectin-binding outer membrane protein CadF
Protein pI	5.71
Protein Weight	36447.78
Protein Length	419
Protein Note	outer membrane beta-barrel protein; TIGR04565
Protein Sequence	>WP_002851185.1 MULTISPECIES: fibronectin-binding outer membrane protein CadF [Campylobacter] MKKIFLCLGLASVLFGADNNVKFEITPTLNYNYFEGNLDMDNRYAPGIRLGYHFDDFWLDQLEFGLEHYS DVKYTNTNKTTDITRTYLSAIKGIDVGEKFYFYGLAGGGYEDFSNAAYDNKSGGFGHYGAGVKFRLSDSL ALRLETRDQINFNHANHNWVSTLGISFGFGGKKEKAVEEVADTRATPQAKCPVEPREGALLDENGCEKTI SLEGHFGFDKTTINPTFQEKIKEIAKVLDENERYDTILEGHTDNIGSRAYNQKLSERRAKSVANELEKYG VEKSRIKTVGYGQDNPRSSNDTKEGRADNRRVDAKFILR
Molecule Role	Protective antigen
Molecule Role Annotation	Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 (Zheng et al., 2007).
Related Vaccines(s)	C. jejuni DNA vaccine pcDNA3.1(+)-cadF
References