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ggt

Gene Name ggt
Sequence Strain (Species/Organism) Helicobacter pylori
NCBI Protein GI ADN80237
Other Database IDs CDD:129176
Taxonomy ID 869727
Gene Strand (Orientation) ?
Protein Name Gamma-glutamyl transpeptidase
Protein pI 9.66
Protein Weight 57541.42
Protein Length 645
Protein Note gamma-glutamyltranspeptidase; TIGR00066
Protein Sequence 
>ADN80237.1 Gamma-glutamyl transpeptidase [Helicobacter pylori 908]
MRRSFLKTIGLGVIALSLGLLNPLSAASYPPIKNTKVGLALSSHPLATEIGQKVLEEGGNAIDAAVAIGF
ALAVVHPAAGNIGGGGFAVIHLANGENVALDFREKAPLKATKNMFLDKQGNVVPKLSEDGYLAAGVPGTV
AGMEAMLKKYGTKKLSQLIDPAIKLAENGYAISQRQAEILKEARERFLKYSSSKKYFFKKGHLDYQEGDL
FVQKDLAKTLNQIKTLGAKGFYQGQVADLIEKDMQKNGGIITKEDLASYNVKWRKPVIGSYRGYKIISMS
PPSSGGTHLIQILNVMENADLSALGYGASKNIHIVAEAMRQAYADRSVYMGDADFVSVPVDKLINKAYAK
KIFDAIQPDTVTPSSQIKPGMGQLHEGSNTTHYSVADRWGNAVSVTYTINASYGSAASIDGAGFLLNNEM
DDFSIKPGNPNLYGLVGGDANAIEANKRPLSSMSPTIVLKNNKVFLVVGSPGGSRIITTVLQVISNVIDY
NMNISEAVSAPRFHMQWLPDELRIEKFGMPADVKDNLTKMGYQIVTKPVMGDVNAIQVLPKTKGSVFYGS
TDPRKEF
Molecule Role Protective antigen
Molecule Role Annotation The highest reduction in bacterial colonization was seen in mice immunized with the fusion protein rHspA-GGT when paired with the mucosal adjuvant LTB. Protection against H. pylori colonization was mediated by a strong systemic and localized humoral immune response (Zhang et al., 2015).
References