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groEL
Gene Name	groEL
Sequence Strain (Species/Organism)	Bacillus anthracis
NCBI Protein GI	KHA39277
Taxonomy ID	1392
Protein Name	molecular chaperone GroEL
Protein pI	4.52
Protein Weight	51999.08
Protein Length	610
Protein Note	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
Protein Sequence	>KHA39277.1 molecular chaperone GroEL [Bacillus anthracis] MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGA KLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGK SSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKME AVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFG DRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQ LEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNV YTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGI VDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGGMGGMM
Molecule Role	Protective antigen
Molecule Role Annotation	(Sinha and Bhatnagar, 2013)
References

groEL