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11C5

Gene Name 11C5
Sequence Strain (Species/Organism) Babesia bovis T2Bo
NCBI Protein GI 156086656
Locus Tag BBOV_IV008150
Protein Accession XP_001610737
Taxonomy ID 484906
Chromosome No 4
Gene Starting Position 946834
Gene Ending Position 948172
Gene Strand (Orientation) +
Protein pI 5.11
Protein Weight 36321.83
Protein Length 346
DNA Sequence 
>NW_001820857.1:946834-948172 Babesia bovis T2Bo chromosome 4 gcontig_1104837696308, whole genome shotgun sequence
TGGCTGACGTCTACCGTCATTTTGACATGCACTGCGTTGCAGCTCGTGCATAGCTTTCGAGTGTTTCATC
TGGGTAAGGGTACAACGTTTTGTCGCGTCAACGTTAAGGCGCATTTCTTCTGATTTTAGCAAGAACGTCG
ACTATATTAAATTCACTTGGTCGGCTTCTTGTGACGCCTACTATTGCTGCGAGAGTGTGTAGGTTTTTCC
TTCAGGCATTACTCTGGAAAATACTATTCGACATACAAGATGTTGGCTACACGTTTTATTTTTAGTCTTT
GCCTATTTGTGGCTCATCAAGGCGTCAACGCCTTTTTCTATCGTGCAGTTCCTATGTACGATCAGAATGG
TAAGCTGGTTCCGGATTCCTCTAATATAGGTCCTTCATCCTTACGAATCGAGGCTACTGGTGTTGGTAGG
ATTTGTTCTACTATGCAATCAGGTATCTATCTCATCAATCCTTACGCTCAGCGCTGCCCAATTGGGAAGA
GCAAATGTGGACCTGAGCATGATTCCACCCTAGGAAAGTGTGCCATGTACTCTGGTTGTTACACCATCAG
TAACGACTTCCGTGCTTGCTCATGCTTGCCTGATTACTTCGGCAACCCTTACAAGCAATGCTTCAGACAC
TGTGACACGGATTTGGACTGCCCTTCACCTTATGCTGAGTGCAGGATGGACGCAGGCGAGACGATCAAGC
GCTGCAAGTGCAGAGCAGGTTGCCCAGGTGATGGTGTCATTTGCAAGCCCGATAAGATCTGTACTGACTT
GGCTGAAGACTCTGAGGCTCACCGTAGGTGCCTTCAGACCGGTATCACCGACAAGACATACGTTTGTGAT
GACGGTTATTACTTGGACACTGATAACAAGTGCCAGCCGATTGTTGAGCTTGAAGATGATAGGGTTGTGA
GCGTAATTGCCAGTGGCTACGTAAACGGCAGCCGTATTGATATTGGTAACTGCTTTTCAATTGAAATTAA
CAAAGACAACGGTATGTCTTACTTCTACCAACTTAACAGTGGTGACCCCGTTGTGATTGACCAAAAAATT
AAGACCGACGACCAGTTGATGTTGTTGTTCGAGGTTAAGGCTAATGACATTATTGCCTTTACCACTACTG
AGGCCAACCCTTCTGGTCTCACTAAAATCTTCACTATCTCAAATGGTCTTAAAGGCTGCAAAATCGACAG
TGTTATGAAGTACTCCCCAACCGGAGCTAAGGAGCACCCCTCAGGTGTCAGGGTTGAGGTTAAAGAGCTT
GAAACTTCGAGCGAAAGGCAGGAGCTTTAGTCAAAATGACGAACCGACTCAAATAGAGTTTAATTTTTTG
TAGAAAATT
Protein Sequence 
>XP_001610737.1 12D3 antigen [Babesia bovis T2Bo]
MLATRFIFSLCLFVAHQGVNAFFYRAVPMYDQNGKLVPDSSNIGPSSLRIEATGVGRICSTMQSGIYLIN
PYAQRCPIGKSKCGPEHDSTLGKCAMYSGCYTISNDFRACSCLPDYFGNPYKQCFRHCDTDLDCPSPYAE
CRMDAGETIKRCKCRAGCPGDGVICKPDKICTDLAEDSEAHRRCLQTGITDKTYVCDDGYYLDTDNKCQP
IVELEDDRVVSVIASGYVNGSRIDIGNCFSIEINKDNGMSYFYQLNSGDPVVIDQKIKTDDQLMLLFEVK
ANDIIAFTTTEANPSGLTKIFTISNGLKGCKIDSVMKYSPTGAKEHPSGVRVEVKELETSSERQEL
Molecule Role Protective antigen
Molecule Role Annotation Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle. Two of these, GST-12D3 and GST-11C5, when used in combination were almost as protective as has been previously shown for the commercially available live attenuated vaccine (Wright et al., 1992).
References