VIOLIN: Vaccine Investigation and Online Information Network

LolA
Gene Name	LolA
Sequence Strain (Species/Organism)	Yersinia pestis CO92
VO ID	VO_0011010
NCBI Gene ID	1174218
NCBI Protein GI	218928525
Locus Tag	YPO1377
Genbank Accession	CP009973
Protein Accession	YP_002346400
Taxonomy ID	214092
Gene Starting Position	1550480
Gene Ending Position	1551088
Gene Strand (Orientation)	+
Protein Name	outer-membrane lipoprotein carrier protein
Protein pI	5.79
Protein Weight	20852.54
Protein Length	202
Protein Note	participates with LolB in the incorporation of lipoprotein into the outer membrane
DNA Sequence	>NC_003143.1:1550480-1551088 Yersinia pestis CO92 chromosome, complete genome AATGAAAAGACTGCTTGTTGCTTGCTGTTTTCTATCGGGTTTGATTTCAGCTTCTGCGTTGGCAGATGCC AGCACAGATCTACAAAATCGGTTGAGTAAAGTGAATAGCTTCCATGCCAGCTTCTCGCAAGCTGTTACCA GTTCAGACGGGGCGGTAGTGCAGGAAGGTGAGGGCGAACTGTGGGTAAAACGTCCTAATTTGTTTAACTG GCATATGACATCACCGGATGAAAGCGTATTAATCTCTGATGGGGAAACTCTGTGGTTTTATAACCCATTT GTTGAACAAGCCACCGCCACTTGGTTGAAGAATGCAACGGGTAATACACCGTTTATGTTGATTACTCGCA ACAACCCAGATGACTGGAAGCAATATAATGTTAAGCAGAAAGGCGATGATTTTGAGCTGACACCTAAAAG TGCTAGCGGCAATTTAAAGCAATTTGCGATAAGTGTGACGCCAAGCGGCACTATCAAAAGCTTTACTGCT GTTGAGCAAGATGGTCAACGCAGTGCTTATACACTGAAAAGCCAGCAAAGTAGCGTGGTTGATGCCAGTA AGTTTACCTTTACTCCCCCAAAAGGTGTGACGCTGGATGATCAGCGGTA
Protein Sequence	>YP_002346400.1 outer-membrane lipoprotein carrier protein [Yersinia pestis CO92] MKRLLVACCFLSGLISASALADASTDLQNRLSKVNSFHASFSQAVTSSDGAVVQEGEGELWVKRPNLFNW HMTSPDESVLISDGETLWFYNPFVEQATATWLKNATGNTPFMLITRNNPDDWKQYNVKQKGDDFELTPKS ASGNLKQFAISVTPSGTIKSFTAVEQDGQRSAYTLKSQQSSVVDASKFTFTPPKGVTLDDQR
Molecule Role	Protective antigen
Molecule Role Annotation	Using a mouse plague model, YPO1377 (lolA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis (Li et al., 2009).
References

LolA