VIOLIN: Vaccine Investigation and Online Information Network

Irp7
Gene Name	Irp7
Sequence Strain (Species/Organism)	Yersinia pestis CO92
VO ID	VO_0011006
NCBI Gene ID	1174753
NCBI Protein GI	218929030
Locus Tag	YPO1914
Genbank Accession	AL590842
Protein Accession	YP_002346905
Taxonomy ID	214092
Gene Starting Position	2165261
Gene Ending Position	2167063
Gene Strand (Orientation)	+
Protein Name	ABC transporter permease
Protein pI	7.2
Protein Weight	61999.23
Protein Length	600
Protein Note	Previously sequenced as Yersinia pestis inner membrane ABC-transporter YbtQ TR:Q9Z375 (EMBL: AL031866) (600 aa) fasta scores: E(): 0, 100.0% id in 600 aa. Similar to Yersinia enterocolitica inner membrane ABC-transporter Irp7 TR:Q9X9I6 (EMBL: AJ132668) (600 aa) fasta scores: E(): 0, 98.8% id in 600 aa
DNA Sequence	>NC_003143.1:2165261-2167063 Yersinia pestis CO92 chromosome, complete genome AATGAAAGACAATAATCCTGCGGATAACCTGGCCTGGCGCGTCATCTGGCGCCAGCTTATCTCCAGCGTT GGCAGTCAGGCCAGGATGCTGCGACGCAGTATGCTGGCGCTGTTGCTGGCGGCATTCATGCAGGGGATCG CCTTTGCCTGTCTTTATCCGATCATTGATGCGCTGTTACGGGGAGACGCGCCGCAACTTCTTAACTGGGC TATGGCCTTCAGCGTCGCCGCAATTGTGACGCTGGTGCTACGCTGGTATGGCCTGGGCTTTGAATACCGT GGTCATCTGGCGCAGGCCACCCATGAGTTGCGCCTGCGACTTGGCGAGCAGTTACGCCGCGTGCCGCTGG AGAAGCTCCAGCGCGGCAGGGCGGGTGAAATGAACGCCTTGCTGCTGGGCAGCGTGGATGAAAACCTCAA TTATGTTATTGCGATAGCCAATATTTTGCTGCTCACCATTGTCACGCCGCTGACGGCGTCGCTGGCGACA TTGTGGATAGACTGGCGGCTGGGGCTGGTGATGTTGCTGATCTTCCCTCTGCTGGTGCCGTTTTATTACT GGCGCCGCCCGGCGATGCGGCGACAAATGCAGACGCTGGGGGAAGCGCACCAGCGTCTGAGCGGCGATAT CGTTGAATTTGCTCAGGGGATGATGGTATTGCGCACCTGCGGCAGCGATGCCGATAAAAGCCGGGCGCTG CTGGCGCATTTCAATGCGCTGGAAAACTTACAGACCCGCACTCACCGTCAGGGCGCTGGCGCGACGATGC TGATCGCCAGCGTCGTGGAGTTGGGCCTACAGGTGGTGGTGTTATCCGGGATCGTCTGGGTAGTGACGGG CACTCTGAACCTCGCCTTTTTGATTGCCGCCGTCGCGATGATTATGCGCTTCGCAGAACCGATGGCGATG TTTATCAGCTACACCTCGGTTGTGGAACTGATCGCCAGCGCCCTGCAACGGATTGAGCGGTTTATGGCGA TAGCACCGCTTCCCGTCGCAGAGCAAAGCGAGATGCCGGAACGTTACGATATCCGCTTTGACAACGTCAG CTATCGCTACGAAGAAGGCGACGGCCACGCGCTTAATCATGTTTCTTTGACGTTCCCGGCAGCCAGTATG AGCGCGCTGGTGGGTGCCTCCGGCGCAGGCAAAACTACGGTCACCAAACTGTTAATGCGCTATGCCGATC CGCAGCAAGGGCAGATTTCTATTGGCGGCGTCGATATTCGCCGCCTGACGCCGGAACAGCTCAATAGCCT GATTTCTGTTGTTTTCCAGGATGTCTGGCTGTTTGATGACACGCTGCTGGCGAATATCCGTATCGCGCGC CCACAGGCGACGCGGCAGGAGGTAGAAGAGGCCGCCCGCGCGGCGCAGTGCCTTGAGTTTATTTCCCGTC TTCCGCAAGGCTGGCTGACGCCAATGGGAGAGATGGGCGGCCAGCTATCGGGCGGCGAGCGCCAGCGGAT TTCCATTGCCAGAGCGTTATTGAAAAACGCGCCGGTCGTCATTCTCGATGAACCGACTGCCGCGCTGGAT ATTGAAAGCGAGCTGGCGGTGCAAAAAGCGATCGATAACCTGGTTCACAACCGGACGGTGATTATCATCG CTCACCGTTTATCCACCATCGCCGGGGCCGGAAACATTCTGGTGATGGAAGAGGGACAGGTGGTTGAGCA GGGTACTCATGCGCAATTGCTCTCACATCATGGACGTTATCAGGCGCTGTGGCAGGCGCAAATGGCCGCG CGCGTGTGGCGCGACGACGGGGTTTCCGCGTCTGGAGAGTGGGTGCATGAGTG
Protein Sequence	>YP_002346905.1 ABC transporter permease [Yersinia pestis CO92] MKDNNPADNLAWRVIWRQLISSVGSQARMLRRSMLALLLAAFMQGIAFACLYPIIDALLRGDAPQLLNWA MAFSVAAIVTLVLRWYGLGFEYRGHLAQATHELRLRLGEQLRRVPLEKLQRGRAGEMNALLLGSVDENLN YVIAIANILLLTIVTPLTASLATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDI VEFAQGMMVLRTCGSDADKSRALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVWVVTG TLNLAFLIAAVAMIMRFAEPMAMFISYTSVVELIASALQRIERFMAIAPLPVAEQSEMPERYDIRFDNVS YRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLLMRYADPQQGQISIGGVDIRRLTPEQLNSL ISVVFQDVWLFDDTLLANIRIARPQATRQEVEEAARAAQCLEFISRLPQGWLTPMGEMGGQLSGGERQRI SIARALLKNAPVVILDEPTAALDIESELAVQKAIDNLVHNRTVIIIAHRLSTIAGAGNILVMEEGQVVEQ GTHAQLLSHHGRYQALWQAQMAARVWRDDGVSASGEWVHE
Molecule Role	Protective antigen
Molecule Role Annotation	Using a mouse plague model, YPO1914 (irp7) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis (Li et al., 2009).
References

Irp7