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guaA
Gene Name	guaA
Sequence Strain (Species/Organism)	Salmonella enterica subsp. enterica serovar Enteritidis str. P125109
NCBI Gene ID	6948075
NCBI Protein GI	207857920
Locus Tag	SEN2490
Genbank Accession	AM933172
Protein Accession	YP_002244571
Taxonomy ID	550537
Gene Starting Position	2623837
Gene Ending Position	2625414
Gene Strand (Orientation)	-
Protein Name	GMP synthase
Protein pI	5.06
Protein Weight	53428.72
Protein Length	525
Protein Note	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
DNA Sequence	>gi\|207855516:2623837-2625414 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 chromosome, complete genome CTTATTCCCACTCAATGGTAGCTGGTGGTTTACCGCTGATGTCATACACCACACGGGAAATCCCGTTGAC TTCATTGATGATGCGGTTGGAAACACGACCCAGGAAATCATACGGCAGATGTGCCCAGTGTGCGGTCATA AAGTCGATGGTTTCGACAGCACGCAGAGAGACAACCCAATCGTACTTACGACCATCGCCCATCACGCCTA CGGAACGGACCGGCAGGAAGACGGTAAACGCCTGACTGACTTTGTCGTACAGATCCGCTTTGCGCAGCTC TTCAATGAAGATAGCGTCCGCGCGACGCAGCAGGTCGCAGTACTCTTTCTTCACTTCGCCCAGTACGCGC ACGCCGAGGCCCGGCCCCGGGAACGGATGGCGATACAGCATGTCGTACGGCAGGCCCAGCTCCAGACCAA TCTTACGCACTTCGTCTTTGAACAGCTCTTTCAGCGGTTCAACCAGCCCCATCTTCATCTCTTTCGGCAG GCCGCCGACATTGTGGTGAGATTTGATGACGTGCGCTTTACCGGTTGCAGACGCCGCAGATTCGATAACG TCAGGGTAGATGGTGCCCTGCGCCAGCCATTTCACGTCTTCCAGTTTCAGCGCTTCTTCGTCGAACACTT CAACGAAAACGCGGCCGATGATCTTACGCTTGGCTTCCGGATCGTTCTCACCAGCCAGCGCGGACAGGAA GCGATCTTCTGCCGGTACGTGAACAATGTTCAGACCAAAATGGTCGCCAAACATGTCCATCACCTGCTCG GCTTCGTTCAGGCGCAACAGGCCGTTGTCGACGAAAACACAGGTCAGATTTTTACCGATCGCGCGGTGCA GCAGCATGGCGGTGACGGAAGAATCCACGCCGCCGGAGAGACCGAGGATCACTTTATCGTCGCCTACCTG CTCGCGAATGCGCGCCACGGCGTCATCGATGATCTTCGCCGGCGTCCACAACGCTTCACACTGGCAGATA TCGCGTACAAAACGCTCCAGCATGCGCATACCCTGGCGGGTGTGAGTCACTTCCGGGTGGAACTGTACGC CGTAGAAGCGTTTTTCTTCGTTGGCCATAATGGCGAACGGGCAGCTCTCGGTGCTGGCGACGGTCACGAA GTCGGACGGAATCGCCGTCACTTTATCGCCGTGGCTCATCCACACGTCCAGCAGCGGTTTGCCGTCTGCG GTCAGGGAATCTTCAATACCGCGAACCAGCGCGCTGTCGGTCAACACTTCGACCTGCGCATAACCAAATT CACGCTCATTAGAACCTTCTACATGACCGCCAAGCTGCATCGCCATGGTCTGCATACCATAGCAAACGCC AAATACCGGCACGCCTGCTTCAAAGACATACTGCGGCGCGCGCGGGCTGTTTTCTTCGGTGGTGCTTTCC GGGCCGCCGGAAAGAATAATGCCGCTTGGGTTGAAGTCACGAATTTGTGCTTCTGTCACATCCCACGCCC ACAGTTCACAGTAAACACCCAGCTCACGCACGCGGCGCGCAACCAGTTGAGTGTACTGAGAACCGAAGTC CAGAATGAGGATGCGATGCTTATGAATGTTTTCCGTCA
Protein Sequence	>gi\|207857920\|ref\|YP_002244571.1\| GMP synthase [Salmonella enterica subsp. enterica serovar Enteritidis str. P125109] MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPR APQYVFEAGVPVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVW MSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTP AKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDH FGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATG KAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEY CDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPY DFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
Molecule Role	Virmugen
Molecule Role Annotation	A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis (Tennant et al., 2011).
Related Vaccines(s)	Salmonella Enteritidis guaBA/clpP mutant vaccine
References

guaA