VIOLIN: Vaccine Investigation and Online Information Network

P1
Gene Name	P1
NCBI Nucleotide GI	27465165
NCBI Protein GI	27465166
Protein Accession	AAN60108.1
Other Database IDs	CDD:100109
Taxonomy ID	5661
Gene Strand (Orientation)	?
Protein Name	ribosomal protein P1-like protein
Protein pI	4.09
Protein Weight	11317.016
Protein Length	182
Protein Note	Ribosomal protein P1. This subfamily represents the eukaryotic large ribosomal protein P1. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P1 is located in the L12 stalk, with proteins...; cd05831
DNA Sequence	>gi\|27465165\|gb\|AY161269.1\| Leishmania donovani ribosomal protein P1-like protein mRNA, complete cds AATTCGTGTACTTTATTAGCACGTCATCACAGAGAACACCTTCCTTACGCACTGTCCATCATCGCCATGT CCGCTGAGACCCTCGCGTGCACGTACGCCGCGCTCATGCTGAGTGACGCCGGCCTGCCCACCTCGGCCGA GAACATCGCCGCGGCGGTGAAGGCGGCCGGCGTCGAGATGCGCCCCACCCTGCCCATCATCTTTGCCCGC TTCCTGGAGAAGAAGTCCGTGGAGACGCTGATGGCGGCCGCCGCCGCGCAGGCCCCGACGGCCGCGTNCG CCCCGTCTCCGGCGGCGGGCGCCGCCTCCGCTGCANCGGNCGGCGGCAAGGTGGAGGACAAGAAGAAGGA CGAGCCTGAGGAAGAGGGCGACGACGACATGGGTTTTGGTCTGTTCGACTGAGCGCCCCGCATGATGACC GGCATATGCGAGCACATGGTTGTTTGGCCTCATGTTCTGCAACACCCGAGCATGCCGTGAGCGCTGCCTC TCTGCGTGCACATATATATATATGTGTGTGTGTGTGTGTGCGTGTGTTTCGCTGCTCTCTTTTTCTTTTC GATTTTATTTACGTGTGCGTTACTCCTTCCTCCTGCGAAAAAAAAAAAAAAAAAAAA
Protein Sequence	>AAN60108.1 ribosomal protein P1-like protein [Leishmania donovani] MSAETLACTYAALMLSDAGLPTSAENIAAAVKAAGVEMRPTLPIIFARFLEKKSVETLMAAAAAQAPTAA XAPSPAAGAASAAXXGGKVEDKKKDEPEEEGDDDMGFGLFD
Molecule Role	Protective antigen
Molecule Role Annotation	DNA vaccine pVAX-P1 in a prime-boost mode was able to induce protection with reduced mortality, a significant (75.68%) decrease in splenic parasite burden and increased expression of Th1 type cytokines in immunized hamsters (Arora et al., 2011).
Related Vaccines(s)	pVAX-P1 DNA vaccine
References

P1