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senA

Gene Name senA
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3671021
NCBI Protein GI 74314887
Locus Tag SSON_P050
Genbank Accession CP000039
Protein Accession YP_313305
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 46479
Gene Ending Position 48176
Gene Strand (Orientation) +
Protein Name OspD3
Protein pI 6.74
Protein Weight 60796.75
Protein Length 565
DNA Sequence 
>gi|74314838:46479-48176 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TATGCCATCAGTAAATTTAATTCCATCAAGGAAAATATGTTTGCAAAATATGATAAATAAAGACAACGTC
TCTGTTGAGACAATCCAGTCTCTATTGCACTCAAAACAATTGCCATATTTTTCTGACAAGAGGAGTTTTT
TATTAAATCTAAATTGCCAAGTTACCGATCACTCTGGAAGACTTATTGTCTGTCGACATTTAGCTTCCTA
CTGGATAGCACAGTTTAACAAAAGTAGTGGTCACGTGGATTATCATCACTTTGCTTTTCCGGATGAAATT
AAAAATTATGTTTCAGTGAGTGAAGAAGAAAAGGCTATTAATGTGCCTGCTATTATTTATTTTGTTGAAA
ACGGTTCATGGGGAGATATTATTTTTTATATTTTCAATGAAATGATTTTTCATTCCGAAAAAAGCAGAGC
ACTAGAAATAAGTACATCAAATCACAATATGGCATTAGGCTTGAAGATTAAAGAAACTAAAAATGGGGGG
GATTTTGTCATTCAGCTTTATGATCCCAACCATACAGCAACTCATTTACGAGCAGAGTTTAACAAATTTA
ACTTAGCTAAAATAAAAAAACTGACTGTAGATAATTTTCTTGATGAAAAACATCAGAAATGTTATGGTCT
TATATCCGACGGTATGTCTATATTTGTGGACAGACATACTCCAACAAGCATGTCCTCCATAATCAGATGG
CCTAATAATTTACTTCACCCCAAAGTTATTTATCACGCGATGCGTATGGGATTGACTGAGCTAATCCAAA
AAGTAACAAGAGTCGTACAACTATCTGACCTTTCAGACAATACGTTAGAATTACTTTTGGCAGCCAAAAA
TGACGATGGTTTGTCAGGATTGCTTTTAGCTTTACAAAATGGGCATTCAGATACAATCTTAGCATACGGA
GAACTCCTGGAAACTTCTGGACTTAACCTTGATAAAACGGTAGAACTACTAACTGCGGAAGGAATGGGAG
GACGAATATCGGGTTTATCCCAAGCACTTCAAAATGGGCATGCAGAAACTATCAAAACATACGGAAGGCT
TCTCAAGAAGAGAGCAATAAATATCGAATACAATAAGCTGAAAAATTTGCTGACCGCTTATTATTATGAT
GAAGTACACAGACAGATACCCGGACTAATGTTTGCTCTTCAAAATGGACATGCAGATGCTATACGCGCAT
ACGGTGAGCTCATTCTTAGCCCCCCTCTCCTCAACTCAGAGGATATTGTAAATTTGCTGGCCTCAAGGAG
ATATGACAATGTTCCCGGACTTCTGTTAGCATTGAATAATGGACAGGCTGATGCAATCTTAGCTTATGGT
GATATCTTGAATGAGGCAAAACTTAACTTGGATAAAAAAGCAGAGCTGTTAGAAGCGAAAGATTCTAATG
GTTTATCTGGATTGTTTGTAGCCTTGCATAATGGATGTGTAGAAACAATTATTGCTTATGGGAAAATACT
TCACACTGCAGACCTTACTCCACATCAGGCATCAAAATTACTGGCAGCAGAAGGCCCAAATGGGGTATCT
GGATTAATTATAGCTTTTCAAAATAGGAATTTTGAGGCAATAAAAACTTATATGGAAATAATAAAAAATG
AAAATATTACACCTGAAGAAATAGCAGAACACTTGGACAAAAAAAATGGAAGTGATTTTCTGGAAATTAT
GAAGAATATAAAAAGCTG
Protein Sequence 
>gi|74314887|ref|YP_313305.1| OspD3 [Shigella sonnei Ss046]
MPSVNLIPSRKICLQNMINKDNVSVETIQSLLHSKQLPYFSDKRSFLLNLNCQVTDHSGRLIVCRHLASY
WIAQFNKSSGHVDYHHFAFPDEIKNYVSVSEEEKAINVPAIIYFVENGSWGDIIFYIFNEMIFHSEKSRA
LEISTSNHNMALGLKIKETKNGGDFVIQLYDPNHTATHLRAEFNKFNLAKIKKLTVDNFLDEKHQKCYGL
ISDGMSIFVDRHTPTSMSSIIRWPNNLLHPKVIYHAMRMGLTELIQKVTRVVQLSDLSDNTLELLLAAKN
DDGLSGLLLALQNGHSDTILAYGELLETSGLNLDKTVELLTAEGMGGRISGLSQALQNGHAETIKTYGRL
LKKRAINIEYNKLKNLLTAYYYDEVHRQIPGLMFALQNGHADAIRAYGELILSPPLLNSEDIVNLLASRR
YDNVPGLLLALNNGQADAILAYGDILNEAKLNLDKKAELLEAKDSNGLSGLFVALHNGCVETIIAYGKIL
HTADLTPHQASKLLAAEGPNGVSGLIIAFQNRNFEAIKTYMEIIKNENITPEEIAEHLDKKNGSDFLEIM
KNIKS
Molecule Role Virmugen
Molecule Role Annotation A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1 (Barnoy et al., 2010).
Related Vaccines(s) Shigella sonnei virG/senA/senB mutant vaccine , Shigella sonnei virG/senA/senB/msbB2 mutant vaccine
References