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wbtA
Gene Name	wbtA
Sequence Strain (Species/Organism)	Francisella tularensis subsp. tularensis SCHU S4
NCBI Gene ID	3191939
NCBI Protein GI	56708505
Locus Tag	FTT_1464c
Genbank Accession	AJ749949
Protein Accession	YP_170401
Taxonomy ID	177416
Gene Starting Position	1514679
Gene Ending Position	1516415
Gene Strand (Orientation)	-
Protein Name	dTDP-glucose 4,6-dehydratase
Protein pI	8.34
Protein Weight	60861.77
Protein Length	578
Protein Note	Similar to Q9S4V4 PglF from Campylobacter jejuni (590 aa). FASTA: opt: 1343 Z-score: 1435.9 E(): 3.9e-72 Smith-Waterman score: 1378; 43.543identity in 604 aa overlap
DNA Sequence	>gi\|255961454:1514679-1516415 Francisella tularensis subsp. tularensis SCHU S4, complete genome ACTACCCATTCAATCTATGTTCAAATTCCGGAACAATTTTCTTTAATATCACAAGCTGATCAACATCATC CTTGATCAACGATTCAATATCTTGGTTTAGAGTATTAATATCGTAAAAAGTCCTTCTACCAATAAAAATA TCTTTATAGTCGGTACTAACATCATCTTCCTCTATCAAAAGCTCTTCGTAAAGTTTCTCTCCTGGACGCA AACCAACTATTTTAATATCAATATCACCTCTACCAGAAAGTCTAATAAATTGTTTAGCAAGATCAATAAT CTTGACAGGTTGCCCCATATCTAAGACAAAGACCTCTGAATTTTTTGCAATAGCACCAGCTTGTAGGACC AGTTCACAAGCTTCTGGTATCAACATAAAATAACGTGTAATTTCAGGATGAGTAACTGTAACAGGACCAC CTTTTCTTATTTGCTCTTCAAATTTTGGAATCACACTGCCACTACTACCAAGCACATTACCAAAACGCAC TGCAGCAAGCTTGGTATTTTTGGGATCAACATTCTGTAAATACAGCTCACAAACTCTCTTGGTAGCCCCC ATAACATTCGTTGGTCGCACTGCTTTATCAGTGGAAATCAATATAAATGACTCAACACCAGCTTCTATAG CCAGATCTATAGCATTCTTAGTACCTAAGATATTATTTCTAATTGCTCTAGAGATATTCTCCTCAACTAA GGGAACATGCTTGTAGGCAGCAGCATGAAATACTATATTTGGAGTATACTTTTGAAAAACCTCAGCCAAT GCTTTTCTATCACAAACAGAACATAGCACACTATTGATATTAAAATGACTACACTCCTCAGTAATTTTAT ATAAGTTAAACTCACTATGATCAACCAATATCAACTCTTTTGCCTGATACTTGATACATTGATGTACTAT TTCAGAACCTATACTACCTCCAGCTCCTGTGACTAGCACCACCTTATTTTTGATAAAATTAGAGATAGAT TCTTTATCTAAACTCTTAGTATCACGCGCTAATAGATCATAGAGTGAAACAGGCTTCAACTGTGACATAA AATTCTCATCTTGAAGAATTTCCTCAAGAGGCGGCATAATTCTAATCTGATTAAAATCCTTTTCAAATTC TTTATATATATTTTTGACTACTTGGTTTGCATTTCTTGGCAATGCAATAACCAAAAGGTCAAATCTACTA GATAGCAATAGTTTTGTTAATTCAGCTTTAGATAGAACCTTTTTACTATCAATACTTCTTTTTTGTAAAG TTTCATTGTCATCAACAAAACATTTGATGCGATAACCAGCAGAAGCAAGTTCTTGAGCAATCTTTGTTCC TGCAGCACCTGCACCATAAATAACCGCAGTTTTACTTTTATCCACTGATCCTCTGTTCATCAAATACCAA TAAAAGTAGACACTTAAACTGATCAAAAAAACATAAAATAAAAACTCAGAGAATATCAACGAAAAAGTGA CTTTGCCATAAAAAAATAATGCCACTATGAAAAATACTGGCAAATTAATAAAAGCCTTACGTAAAAAAGT TTTTTGAGTCGACTTACGCCAACTAGCCATATAATCTCTAAGTAGTAAAAAAGATGACAAGCATCTCAGC AAAACTAATGCAAGTAAAAAATGTAAATTAACATCTTGCTTGAAAATATAGAAAGTCCAATTAACAGTAA TAATAGTTAAAACTATTATTACCACGAAATTAAGCGTTCTATTATCGTAGAAAGACA
Protein Sequence	>gi\|56708505\|ref\|YP_170401.1\| dTDP-glucose 4,6-dehydratase [Francisella tularensis subsp. tularensis SCHU S4] MSFYDNRTLNFVVIIVLTIITVNWTFYIFKQDVNLHFLLALVLLRCLSSFLLLRDYMASWRKSTQKTFLR KAFINLPVFFIVALFFYGKVTFSLIFSEFLFYVFLISLSVYFYWYLMNRGSVDKSKTAVIYGAGAAGTKI AQELASAGYRIKCFVDDNETLQKRSIDSKKVLSKAELTKLLLSSRFDLLVIALPRNANQVVKNIYKEFEK DFNQIRIMPPLEEILQDENFMSQLKPVSLYDLLARDTKSLDKESISNFIKNKVVLVTGAGGSIGSEIVHQ CIKYQAKELILVDHSEFNLYKITEECSHFNINSVLCSVCDRKALAEVFQKYTPNIVFHAAAYKHVPLVEE NISRAIRNNILGTKNAIDLAIEAGVESFILISTDKAVRPTNVMGATKRVCELYLQNVDPKNTKLAAVRFG NVLGSSGSVIPKFEEQIRKGGPVTVTHPEITRYFMLIPEACELVLQAGAIAKNSEVFVLDMGQPVKIIDL AKQFIRLSGRGDIDIKIVGLRPGEKLYEELLIEEDDVSTDYKDIFIGRRTFYDINTLNQDIESLIKDDVD QLVILKKIVPEFEHRLNG
Molecule Role	Virmugen
Molecule Role Annotation	A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B (Sebastian et al., 2007).
Related Vaccines(s)	Francisella tularensis wbtA mutant vaccine
References

wbtA