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clpB

Gene Name clpB
Sequence Strain (Species/Organism) Francisella tularensis subsp. tularensis SCHU S4
NCBI Gene ID 3192509
NCBI Protein GI 56708764
Locus Tag FTT_1769c
Genbank Accession AJ749949
Protein Accession YP_170660
3D structure: PDB ID 3P2L
Taxonomy ID 177416
Gene Starting Position 1857727
Gene Ending Position 1860306
Gene Strand (Orientation) -
Protein Name ClpB protein
Protein pI 5.27
Protein Weight 89876.23
Protein Length 859
Protein Note Similar to FASTA: AAO89660 (Q83F55) ClpB protein from Coxiella burnetii (859 aa). FASTA: opt: 3593 Z-score: 3223.6 E(): 1.1e-171 Smith-Waterman score: 3593; 65.357 identity in 840 aa overlap
DNA Sequence 
>gi|255961454:1857727-1860306 Francisella tularensis subsp. tularensis SCHU S4, complete genome
TTTATTTAGAGAATATAATATTGTTATTAGCGTCAATATCGACAACTATTTTATCTTCAGCTTTAAACTC
ACCATCTAGAAGTTTTAGAGCCAGAGGGTTTTCTAAGTTGTTTTGAATAGCGCGCTTAAGCGGTCTAGCA
CCAAACACAGGATCAAAGCCAGCATCAGCTAGTTTATCCATAGCTCCAGTTGTGACTTCTAATCCTATAC
TTAGATCTGCTAGACGTTTTTCTAAGCGTTTGATTTGTATTTTAGCTATTTCAGTTATCATCTCTTTGTT
TAGAGGTTCAAAGACAATTGCATCATCAACTCTATTTACAAATTCAGGTCTAAAGTGGCTAAGTACCATT
TCCATTACAGCAGATTTTACTGTTTCATAATCCTGACCTTGCATTTCTTGGATTCGATGTGAACCAAGGT
TAGAAGTCATAACTATTACAGTATTTTTAAAGTCTACTGTTCTGCCTTGCCCATCTGTTAGGCGACCATC
GTCAAGCACTTGTAGTAAGATGTTAAATATATCAGCATGAGCTTTTTCAACCTCATCAAGTAAGATTACA
GAATAAGGTTTTCTTCTAACATGTTCAGTTAGATAGCCGCCTTGTTCATAACCTACGTATCCAGGAGGTG
CGCCTATTAGTCTAGCTACAGAATGTTTCTCCATAAACTCAGACATATCTACTCTAAGCATGGCATCTTC
ATCATCAAACAAAAACTCTGCTAAAGCTTTTGTAAGCTCAGTTTTACCGACACCAGTTGGACCTAAGAAC
ATGAATGAGCCTATAGGTCTATTTGGATCTGATAATCCAGAACGAGATCTTCTTACAGCATTTGATACTG
CTTTTATAGCTTGATCTTGTCCGATTACTCTTTTATGTAAGAAACTTTCCATATTTAGAAGCTTGTCTTT
TTCGCCTTCCATCATCTTAGACACAGGTATTCCAGTAGCTTTTGAAACTACATCAGCAATCTCATTTTCT
GTAACAGATGTTCTTACTAATTTGTTTTCAGAAGGTTCTGCTTCAGTTTCTTCTATTTGTTTAATTTGTG
CTTCTAGCTCAGGTATTTTACCGTATTGTAATTCTGCCATTTTGCTCAAATCACCCACTCTTTGGTACTT
TTCAAGTTCAAACTTGGCTTTCTCAAGCTCTTCTTTTAGTTTACTTGTACCTTGCATCTTAAGCTTTTCA
GCTTTCCAAAGCTCTTCTAGTCCTTTATACTCGGAGTCTAGCCCTTTTATTTCTTGCTCAAGTATCTCTA
AACGTTTTTTAGTAGCATCATCTTTCTCTTTCTTTAGCTGTTCGCGTTGCATTTTCAGCTGGATGATTCT
ACGATATAAGCTTTCCATTTTTTCAGGTTTAGAGTCTATTTCCATACGAATTTGGCTTGCTGCTTCATCT
ACTAGATCTATAGCTTTATCAGGTAGCTGTCTATCTGTGATATACCTATGTGACAAAGTTGCTGCACTTA
CAATAGCTGAATCTGTGATATTTACACCATGATGTAGCTCATATCTTTCTTTTAGGCCTCTAAGTATAGC
GATAGTATCTTCTACAGTAGGTTCATCAACTAGCACTTTCTGGAATCTTCGCTCAAGTGCCGGATCTTTT
TCAACATACTCACGATACTCATCTAAAGTTGTTGCACCAACACACTTTAGCTCTCCTCTAGCTAGAGCAG
GTTTAAGCATGTTACCAGCATCCATAGATCCTTCTGCTTTACCAGCACCTACCATAGTATGTAATTCATC
TATAAAGAGAATTACATTACCTTCTTGTTTTGATAACTCTTTTAATACAGATTTTAGACGCTCTTCAAAA
TCTCCTCTAAATTTAGCACCAGCTAGCAGTGCACCCATATCTAATGATAGTACTTTTTTACCTTTGACAC
CTTCTGGTACTTCATCATTAACTATTCGTTGAGCTAAGCCCTCAACAATAGCAGTTTTACCAACACCAGG
CTCACCTATAAGCACAGGGTTGTTCTTAGTTCTTCTTTGTAATACTTGAATAGTTCTACGGATCTCACTA
TCTCTACCGATTATTGGATCAATTTTTCCTTTTCTCGCTAGATCAGTTAGATCTACCGTGTATTTATCTA
ATGCACCTTTCATATCTTCTTGATTTTGACTACTCACTTTCTCCCCTCCGCGATAATCATTGACTGCTTT
TGTTAATTTTTCTTTTGTAATACCAAATTTGTTATACAGTCCAGTTAAACTTTTGTCTTCTAAAGAGGCT
AATAAGAAAACCTCACTCGAGATAAACTCATCACCATTTTTATTAGCAAGCCCTTGCATTTTATGTAATG
TAGCTATTAAATCTCTAGATGGTGTTACTTGAGGGTTACCTTCTCCAGATAATACCGCAACACTATCAAC
CATATCATTTACAGCTTTTATAAAGTTTTGTATATTAACACCACAAACGCTTAATATAGATATAGCAACA
CTATCATTTTGCTCCAAAAGAGCTTTTAGTATATGTGCTGATGTAAACTCAGTTGCTTTTTGTTGAAAAG
CATAAGATTGAGCCTCAGCTAGAGCTTCTTGTAGTTTTATTGTAAATTTATTTATATCCA
Protein Sequence 
>gi|56708764|ref|YP_170660.1| ClpB protein [Francisella tularensis subsp. tularensis SCHU S4]
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDS
VAVLSGEGNPQVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAV
NDYRGGEKVSSQNQEDMKGALDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGV
GKTAIVEGLAQRIVNDEVPEGVKGKKVLSLDMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDEL
HTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYREYVEKDPALERRFQKVLVDEPTVEDTIAIL
RGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQIRMEIDSKPEKMESLYRRII
QLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELEKAKFELEKYQ
RVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDK
LLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDA
MLRVDMSEFMEKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEVEKAHADIFNILLQVLDDGR
LTDGQGRTVDFKNTVIVMTSNLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKE
MITEIAKIQIKRLEKRLADLSIGLEVTTGAMDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFK
AEDKIVVDIDANNNIIFSK
Molecule Role Virmugen
Molecule Role Annotation A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice (Conlan et al., 2010).
Related Vaccines(s) Francisella tularensis clpB mutant vaccine
References