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Vaccine Comparison

ALVAC- CDV-H/F NYVAC- CDV-H/F PUREVAXFerret Distemper
Vaccine Information Vaccine Information Vaccine Information
  • Vaccine Ontology ID: VO_0004773
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • CDVgp6 haemagglutinin protein H gene engineering:
    • Type: Recombinant vector construction
    • Description: Attenuated vaccinia virus (NYVAC) or canarypox virus (ALVAC) vaccine strains expressing the CDV hemagglutinin (H) and fusion (F) protein genes (NYVAC-HF and ALVAC-HF) (Welter et al., 2000).
    • Detailed Gene Information: Click Here.
  • CDVgp5 gene engineering:
    • Type: Recombinant protein preparation
    • Description: Attenuated vaccinia virus (NYVAC) or canarypox virus (ALVAC) vaccine strains expressing the CDV hemagglutinin (H) and fusion (F) protein genes (NYVAC-HF and ALVAC-HF) (Welter et al., 2000).
    • Detailed Gene Information: Click Here.
  • Vector:
  • Preparation: An attenuated canarypox virus (ALVAC) vaccine strain expressing the CDV hemagglutinin (H) and fusion (F) protein genes (ALVAC-HF) (Welter et al., 2000).
  • Immunization Route: intranasal immunization
  • Vaccine Ontology ID: VO_0004772
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • CDVgp6 haemagglutinin protein H gene engineering:
    • Type: Recombinant vector construction
    • Description: Attenuated vaccinia virus (NYVAC) or canarypox virus (ALVAC) vaccine strains expressing the CDV hemagglutinin (H) and fusion (F) protein genes (NYVAC-HF and ALVAC-HF) (Welter et al., 2000).
    • Detailed Gene Information: Click Here.
  • CDVgp5 gene engineering:
    • Type: Recombinant vector construction
    • Description: Attenuated vaccinia virus (NYVAC) or canarypox virus (ALVAC) vaccine strains expressing the CDV hemagglutinin (H) and fusion (F) protein genes (NYVAC-HF and ALVAC-HF) (Welter et al., 2000).
    • Detailed Gene Information: Click Here.
  • Vector:
  • Preparation: An attenuated vaccinia virus (NYVAC) vaccine strain expressing the CDV hemagglutinin (H) and fusion (F) protein genes (NYVAC-HF) (Welter et al., 2000).
  • Immunization Route: Intramuscular injection (i.m.)
  • Tradename: PUREVAXFerret Distemper
  • Manufacturer: Merial
  • Vaccine Ontology ID: VO_0001159
  • Type: Recombinant vector vaccine
  • Status: Licensed
  • Vector:
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: Canarypox virus-vectored vaccine
References References References
Welter et al., 2000: Welter J, Taylor J, Tartaglia J, Paoletti E, Stephensen CB. Vaccination against canine distemper virus infection in infant ferrets with and without maternal antibody protection, using recombinant attenuated poxvirus vaccines. Journal of virology. 2000; 74(14); 6358-6367. [PubMed: 10864646].
Welter et al., 2000: Welter J, Taylor J, Tartaglia J, Paoletti E, Stephensen CB. Vaccination against canine distemper virus infection in infant ferrets with and without maternal antibody protection, using recombinant attenuated poxvirus vaccines. Journal of virology. 2000; 74(14); 6358-6367. [PubMed: 10864646].