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iap

General Information
Protegen ID 862
Sequence Strain (Species/Organism) Listeria monocytogenes strain L2K3-549C1
VO ID VO_0012404
Taxonomy ID 1639
Other Database IDs CDD:333284
Molecule Role Protective antigen
Molecule Role Annotation Mice immunized with p60 encapsulated in liposomes launched a strong CTL response and were protected against a subsequent challenge with L. monocytogenes (Grenningloh et al., 2008).
Related Vaccines(s) L. monocytogenes p60 Protein Vaccine
References
Grenningloh et al., 2008: Grenningloh R, Darj A, Bauer H, zur Lage S, Chakraborty T, Jacobs T, Weiss S. Liposome-encapsulated antigens induce a protective CTL response against Listeria monocytogenes independent of CD4+ T cell help. Scandinavian journal of immunology. 2008; 67(6); 594-602. [PubMed: 18433404].
Gene Information
Gene Name iap
Protein Information
Protein Name p60
NCBI Protein GI 215422507
Protein pI 10.49
Protein Weight 13324.02
Protein Length 182
Protein Note Cell wall-associated hydrolase, NlpC family [Cell wall/membrane/envelope biogenesis]; cl28464
Protein Sequence 
>BAG85375.1 p60, partial [Listeria monocytogenes]
MSWNNLSSSSIYVGQKLAIKQTANTVTPKAEVKKEAPAAEKQAAPVVKENTNTNTNTTTEKKETTQQQTA
PKAPTEAAKPAPAPSTNTNANKTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGS
Epitope Information
IEDB Linear Epitope