VIOLIN: Vaccine Investigation and Online Information Network

esxV

General Information

Protegen ID

4396

Sequence Strain (Species/Organism)

Mycobacterium tuberculosis H37Rv

Taxonomy ID

83332

Other Database IDs

CDD:310537

Molecule Role

Protective antigen

Molecule Role Annotation

ID93/GLA-SE protects against TB and MDR-TB in animals.(Bertholet et al., 2010)

Related Vaccines(s)

ID93/GLA-SE

References

Bertholet et al., 2010: Bertholet S, Ireton GC, Ordway DJ, Windish HP, Pine SO, Kahn M, Phan T, Orme IM, Vedvick TS, Baldwin SL, Coler RN, Reed SG. A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis. Science translational medicine. 2010; 2(53); 53ra74. [PubMed: 20944089].

Gene Information

Gene Name

esxV

Protein Information

Protein Name

ESAT-6 like protein EsxV

NCBI Protein GI

NP_218136

Protein pI

4.62

Protein Weight

10489.63

Protein Length

170

Protein Note

Proteins of 100 residues with WXG; pfam06013

Protein Sequence

>NP_218136.1 ESAT-6 like protein EsxV [Mycobacterium tuberculosis H37Rv]
MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANA
HGQKVQAAGNNMAQTDSAVGSSWA

Epitope Information

IEDB Linear Epitope