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Vaccine Comparison
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RB51--MIC3/GRA2/GRA6/MIC1/SRS2 |
RB51-SRS2 |
| Vaccine Information |
Vaccine Information |
- Vaccine Ontology ID: VO_0004649
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- MIC1
gene engineering:
- Type: Recombinant vector construction
- Description: Neospora caninum protective antigens MIC1, MIC3, GRA2, GRA6 and RS2 were expressed in strain RB51 (Ramamoorthy et al., 2007).
- Detailed Gene Information: Click Here.
- SRS2
gene engineering:
- Type: Recombinant vector construction
- Description: Neospora caninum protective antigens MIC1, MIC3, GRA2, GRA6 and RS2 were expressed in strain RB51 (Ramamoorthy et al., 2007).
- Detailed Gene Information: Click Here.
- GRA6
gene engineering:
- Type: Recombinant vector construction
- Detailed Gene Information: Click Here.
- Vector:
- Preparation: A recombinant strain RB51 expressing N. caninum antigen. Neospora caninum protective antigens MIC1, MIC3, GRA2, GRA6 and SRS2 were expressed in strain RB51 (Ramamoorthy et al., 2007).
- Immunization Route: Intramuscular injection (i.m.)
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- Vaccine Ontology ID: VO_0004648
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- SRS2
gene engineering:
- Type: Recombinant vector construction
- Description: Recombinant RB51 strains each expressing SRS2 (RB51/SRS2) or GRA7 (RB51/GRA7) antigens of N. caninum (Alaeddine et al., 2005).
- Detailed Gene Information: Click Here.
- Vector:
- Preparation: RB51 strains expressing SRS2 (RB51/SRS2) or GRA7 (RB51/GRA7) antigens of N. caninum (Vemulapalli et al., 2007).
- Immunization Route: Intramuscular injection (i.m.)
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| References |
References |
Ramamoorthy et al., 2007: Ramamoorthy S, Sanakkayala N, Vemulapalli R, Jain N, Lindsay DS, Schurig GS, Boyle SM, Sriranganathan N. Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens. International journal for parasitology. 2007; 37(13); 1531-1538. [PubMed: 17575983].
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Alaeddine et al., 2005: Alaeddine F, Keller N, Leepin A, Hemphill A. Reduced infection and protection from clinical signs of cerebral neosporosis in C57BL/6 mice vaccinated with recombinant microneme antigen NcMIC1. The Journal of parasitology. 2005; 91(3); 657-665. [PubMed: 16108562].
Vemulapalli et al., 2007: Vemulapalli R, Sanakkayala N, Gulani J, Schurig GG, Boyle SM, Lindsay DS, Sriranganathan N. Reduced cerebral infection of Neospora caninum in BALB/c mice vaccinated with recombinant Brucella abortus RB51 strains expressing N. caninum SRS2 and GRA7 proteins. Veterinary parasitology. 2007; 148(3-4); 219-230. [PubMed: 17651896].
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