Vaxvec

Vaccine Comparison

RB51--MIC3/GRA2/GRA6/MIC1/SRS2	RB51-SRS2
Vaccine Information	Vaccine Information
Vaccine Ontology ID: VO_0004649 Type: Recombinant vector vaccine Status: Research Host Species for Licensed Use: Baboon MIC1 gene engineering: Type: Recombinant vector construction Description: Neospora caninum protective antigens MIC1, MIC3, GRA2, GRA6 and RS2 were expressed in strain RB51 (Ramamoorthy et al., 2007). Detailed Gene Information: Click Here. SRS2 gene engineering: Type: Recombinant vector construction Description: Neospora caninum protective antigens MIC1, MIC3, GRA2, GRA6 and RS2 were expressed in strain RB51 (Ramamoorthy et al., 2007). Detailed Gene Information: Click Here. GRA6 gene engineering: Type: Recombinant vector construction Detailed Gene Information: Click Here. Vector: Brucella abortus strain RB51 vaccine vector Vactor Name: Brucella abortus strain RB51 vaccine vector VO ID: VO_0000020 Preparation: A recombinant strain RB51 expressing N. caninum antigen. Neospora caninum protective antigens MIC1, MIC3, GRA2, GRA6 and SRS2 were expressed in strain RB51 (Ramamoorthy et al., 2007). Immunization Route: Intramuscular injection (i.m.)	Vaccine Ontology ID: VO_0004648 Type: Recombinant vector vaccine Status: Research Host Species for Licensed Use: Baboon SRS2 gene engineering: Type: Recombinant vector construction Description: Recombinant RB51 strains each expressing SRS2 (RB51/SRS2) or GRA7 (RB51/GRA7) antigens of N. caninum (Alaeddine et al., 2005). Detailed Gene Information: Click Here. Vector: Brucella abortus strain RB51 vaccine vector Vactor Name: Brucella abortus strain RB51 vaccine vector VO ID: VO_0000020 Preparation: RB51 strains expressing SRS2 (RB51/SRS2) or GRA7 (RB51/GRA7) antigens of N. caninum (Vemulapalli et al., 2007). Immunization Route: Intramuscular injection (i.m.)
References	References
*Ramamoorthy et al., 2007:* Ramamoorthy S, Sanakkayala N, Vemulapalli R, Jain N, Lindsay DS, Schurig GS, Boyle SM, Sriranganathan N. Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens. International journal for parasitology. 2007; 37(13); 1531-1538. [PubMed: 17575983].	*Alaeddine et al., 2005:* Alaeddine F, Keller N, Leepin A, Hemphill A. Reduced infection and protection from clinical signs of cerebral neosporosis in C57BL/6 mice vaccinated with recombinant microneme antigen NcMIC1. The Journal of parasitology. 2005; 91(3); 657-665. [PubMed: 16108562]. *Vemulapalli et al., 2007:* Vemulapalli R, Sanakkayala N, Gulani J, Schurig GG, Boyle SM, Lindsay DS, Sriranganathan N. Reduced cerebral infection of Neospora caninum in BALB/c mice vaccinated with recombinant Brucella abortus RB51 strains expressing N. caninum SRS2 and GRA7 proteins. Veterinary parasitology. 2007; 148(3-4); 219-230. [PubMed: 17651896].