VIOLIN: Vaccine Investigation and Online Information Network

AS02
Vaxjo ID	26
Vaccine Adjuvant Name	AS02
Adjuvant VO ID	VO_0001264
Description	AS02 is a combination adjuvant of the oil-in-water emulsion MF59 with MPL and the saponin fraction QS21(McKee et al., 2007).
Stage of Development	Clinical Trial
Related Vaccine(s)	Subunit vaccine FMP1/AS02A (Plasmodium spp.) M. tuberculosis Mtb72F Protein Subunit Vaccine (Mycobacterium tuberculosis) RTS,S/AS02A (Plasmodium spp.) Fusion protein with adjuvant Mtb72f fusion protein (Mycobacterium tuberculosis)
References	*McKee et al., 2007:* McKee AS, Munks MW, Marrack P. How do adjuvants work? Important considerations for new generation adjuvants. Immunity. 2007; 27(5); 687-690. [PubMed: 18031690].