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Trichinella spiralis

Table of Contents
  1. Protective Antigens
    1. cathepsin B2
    2. Glutathione-S-transferase (GST)
1. cathepsin B2
  • Gene Name : cathepsin B2
  • Sequence Strain (Species/Organism) : Trichinella spiralis
  • NCBI Protein GI : ARG41449
  • Other Database IDs : CDD:312252
    CDD:239111
  • Taxonomy ID : 6334
  • Protein Name : cathepsin B2
  • Protein pI : 8.29
  • Protein Weight : 59776.22
  • Protein Length : 608
  • Protein Note : Oligosaccharide biosynthesis protein Alg14 like; pfam08660
  • Protein Sequence : Show Sequence
    >ARG41449.1 cathepsin B2 [Trichinella spiralis]
    MSFFICAFICFCVCFSLLLIVRYRRHLRHRRTNSTVSTCVVLGSGGHTMEILRLVQSLDNSKYNPIHFII
    ADTDSNSVEKVKPMLKDDNVSFSTIRRCREVKQSISNVFLPTLVATGQSLVQIWRTKPELLLCNGPGTCL
    PVCFAAFFVDLLFGRTCRIIYVESVCRVTRLSLTCKILYYFYLADHVLVQWPELAAVYPRTLYIGSLFVF
    ALAENYEENYERLKVELERQRQANGNTFSWKFGRNAYFKNKSIGEIKKLLGYRMLPKTVKERNEMPMPED
    LLNLENFNYPVEFDSRKHWPQCEKVISFIKDQANCGSCWAVSSASVMSDRTCIATDGQFTTLLSDAELLS
    CCTSCGYGCNGGYPQRTFKYWVYSGMPTGGPYGSNDTCKPYPIPPCSNCSETRTPKCSKSCISTYPLSLN
    EDRHYGSTYYQFWLGEKSMMKDISLYGPIVAGMSVYEDFLHYKEGVYTQESGIFLGGHAVRIIGWGEQDN
    IPYWLVANSWNTTFGEDGLFKIRRGFDECGIESYVSAGRAKCKQNISNNFNSFKYKISIEN
    
    
  • Molecule Role : Protective antigen
  • Molecule Role Annotation : (Yang et al., 2018)
2. Glutathione-S-transferase (GST)
  • Gene Name : Glutathione-S-transferase (GST)
  • Sequence Strain (Species/Organism) : Trichinella spiralis
  • NCBI Protein GI : ABA42914
  • Other Database IDs : CDD:294274
    CDD:173353
    CDD:295467
    CDD:198286
  • Taxonomy ID : 6334
  • Protein Name : glutathione-S-transferase
  • Protein pI : 6.52
  • Protein Weight : 23413.26
  • Protein Length : 270
  • Protein Note : Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
  • Protein Sequence : Show Sequence
    >ABA42914.1 glutathione-S-transferase [Trichinella spiralis]
    MPLYKLVYFPIRGLAEPIRLLLHDQRVEFLDNRIQQKDWPEIKSQMLFGQVPCLYEDDQPIVQSGAIMRH
    LGRRFGLYGNAEEMTYVDQIYEGVVDLRLKYARLIYSDSFHESKGKFINEVLPDELAKFEKILTGKKYIL
    DDEITFADYALAELLDVLLILSSSCLENFTALTIYHSRFMNRPNLKRYLSSDIRKNAKINGNENK
    
    
  • Molecule Role : Protective antigen
  • Molecule Role Annotation : (Liu et al., 2017)
II. References
1. Liu et al., 2017: Liu CY, Song YY, Ren HN, Sun GG, Liu RD, Jiang P, Long SR, Zhang X, Wang ZQ, Cui J. Cloning and expression of a Trichinella spiralis putative glutathione S-transferase and its elicited protective immunity against challenge infections. Parasites & vectors. 2017; 10(1); 448. [PubMed: 28962639].
2. Yang et al., 2018: Yang Z, Li W, Yang Z, Pan A, Liao W, Zhou X. A novel antigenic cathepsin B protease induces protective immunity in Trichinella-infected mice. Vaccine. 2018; 36(2); 248-255. [PubMed: 29199042].