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Yersinia enterocolitica

Table of Contents
  1. Protective Antigens
    1. LcrV
1. LcrV
  • Gene Name : LcrV
  • Sequence Strain (Species/Organism) : Yersinia enterocolitica
  • VO ID : VO_0011321
  • NCBI Gene ID : 1449458
  • NCBI Protein GI : 32470278
  • Locus Tag : pYVe8081_p09
  • Genbank Accession : CP009845
  • Protein Accession : NP_863514
  • Taxonomy ID : 630
  • Plasmid No : pYVe8081
  • Gene Starting Position : 12283
  • Gene Ending Position : 13257
  • Gene Strand (Orientation) : -
  • Protein Name : LcrV
  • Protein pI : 5.5
  • Protein Weight : 35777.8
  • Protein Length : 324
  • DNA Sequence : Show Sequence 
    >NC_005017.1:12283-13257 Yersinia enterocolitica 8081 plasmid pYVe8081, complete sequence
ATTACCTCGTGTCATCTAGCAGACGTTGCATTACTGAATCATATTTCTGAATGAAACGGTTCAGTGCTTC
AATAGCTGAATTAAAACGTGATGTAATATCAGACAGCTGAGTTGTTTTTTGGCTAACCAAGTCGTTGAGC
GGCCTGGACTTATCCGAGCAGGCGGTGGCAAAGTGAGATAATTCATTATTATCTTTATTATAAGAGTATG
AATTTTTCAGGTTACCCAACGCCCCGGTTCTTTTATTCTCACTTTCAAGAAAGTTCTTTATCGAGACTAT
TTTTTTTTCGGTCTCACCTTCCTTAATGGTGGTTTGAGACATTTTCTCAAGAATTTTGTACTCTGCGCTG
GCTTTAAAAATCTCTTCATCTGTATAACCATATAAATTTTTATCCATGAGATTAATTGATTTATCATGGA
TATTTATGGTGCCACTATTCGACAGATACTTATTAATTTCAGCTTGAATAACTGAATAAATTTTTAATTC
GGCGGTAAGCTCAGCTAATTCTTCACGCAACTTGCTACGGGCATCACCATGATGATTCATTGAATCAACA
ATCACTTTCAAAATATCATCATCGATACGATCGGCGGTTAAAGAGAAATGCATTACTGCCATGAACGCTC
GCAACTCCCATTGTGTATTCGGCGATGATTCAAGGAACTCTTTTACTCGCTTGATGCCATTTTGCAGTTG
GTTGTCATAATGACCGCCTTTAAGAATGGCATCCTCGGGTAGAAAATAAGCCAGGATTTTCTTGAGTAAT
TCGATATCATCAGTAATTACCCTTTCGGCAAAAACCTCCGAATCTTTTTTGGGATCATATTTAATGGAAA
TATCTATCTTTTTATCTTTGACTAACTGAACCAATTCTTCTAAAACTGAAGAACCATGACCAGTAAGTTG
TTCCACCCTAACTTTTTCTAGATCCTCAATAAAATGTTGTGGGTTTTGTTCGTAGGCTCTAATCA
  • Protein Sequence : Show Sequence 
    >NP_863514.1 LcrV (plasmid) [Yersinia enterocolitica]
MIRAYEQNPQHFIEDLEKVRVEQLTGHGSSVLEELVQLVKDKKIDISIKYDPKKDSEVFAERVITDDIEL
LKKILAYFLPEDAILKGGHYDNQLQNGIKRVKEFLESSPNTQWELRAFMAVMHFSLTADRIDDDILKVIV
DSMNHHGDARSKLREELAELTAELKIYSVIQAEINKYLSNSGTINIHDKSINLMDKNLYGYTDEEIFKAS
AEYKILEKMSQTTIKEGETEKKIVSIKNFLESENKRTGALGNLKNSYSYNKDNNELSHFATACSDKSRPL
NDLVSQKTTQLSDITSRFNSAIEALNRFIQKYDSVMQRLLDDTR
  • Molecule Role : Protective antigen
  • Molecule Role Annotation : Mice actively immunized using a recombinant V antigen (rVagHis, encoded by lcrV gene) of Y. enterocolitica were completely protected against challenge with both, Y. enterocolitica 0:8 and Y. pseudotuberculosis serotype III (Schmidt et al., 1999).
  • Related Vaccine(s): Y. enterocolititica Subunit V Antigen Protein Vaccine
II. References
1. Schmidt et al., 1999: Schmidt A, Schaffelhofer S, Müller K, Röllinghoff M, Beuscher HU. Analysis of the Yersinia enterocolitica 0:8 V antigen for cross protectivity. Microbial pathogenesis. 1999; 26(4); 221-233. [PubMed: 10089162].