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ELI-Ag1

General Information
Protegen ID 798
Sequence Strain (Species/Organism) Coccidioides immitis
VO ID VO_0011329
Taxonomy ID 5501
Molecule Role Protective antigen
Molecule Role Annotation ELI-Antigen 1 (ELI-Ag1) was tested for its protective capacity in BALB/c mice against intraperitoneal challenge with 2500 arthroconidia of this dimorphic fungus and was found to be highly protective (Ivey et al., 2003).
References
Ivey et al., 2003: Ivey FD, Magee DM, Woitaske MD, Johnston SA, Cox RA. Identification of a protective antigen of Coccidioides immitis by expression library immunization. Vaccine. 2003; 21(27-30); 4359-4367. [PubMed: 14505918].
Gene Information
Gene Name ELI-Ag1
Protein Information
Protein Name expression library immunization antigen 1
NCBI Protein GI 37779128
Protein pI 5.13
Protein Weight 21683.39
Protein Length 306
Protein Sequence
>AAO62547.1 expression library immunization antigen 1 [Coccidioides immitis]
MHLSGIVFAFSALISLSTAHFRLVDPPPRGFSEDMLTRFPCGGQSMSKSRTSVSLTDLEMPIALEMGHDQ
TAVQVLLALGSHPGSNFNITLVPTFRQVGLGDFCLPSVSLDEQRLGVKPVDGMNATLQVVTNGDPNGGLY
NCADITFSSTTEYTVPSSCKNGTGVAATPFSGEAATRNANESTPNGQPQRGNSGSGPTSNIAGHLETATW
GVLGAIVVGGVALL

Epitope Information
IEDB Linear Epitope