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SCGB2A2

General Information
Protegen ID 722
Sequence Strain (Species/Organism) Homo sapiens
Taxonomy ID 9606
Molecule Role Protective antigen
Molecule Role Annotation Passive transfer of mammaglobin-A-reactive CTLs into SCID (severe combined immunodeficient) beige mice with actively growing mammaglobin-A+ tumors resulted in statistically significant regression (P<.001) in the growth of the tumors (Narayanan et al., 2004).
References
Narayanan et al., 2004: Narayanan K, Jaramillo A, Benshoff ND, Campbell LG, Fleming TP, Dietz JR, Mohanakumar T. Response of established human breast tumors to vaccination with mammaglobin-A cDNA. Journal of the National Cancer Institute. 2004; 96(18); 1388-1396. [PubMed: 15367572].
Gene Information
Gene Name SCGB2A2
NCBI Gene ID 4250
Genbank Accession AF015224
Chromosome No 11
Gene Starting Position 62270129
Gene Ending Position 62273159
DNA Sequence 
>NC_000011.10:62270129-62273159 Homo sapiens chromosome 11, GRCh38.p12 Primary Assembly
AAATAGAGCAAGGCTGGGTGCTCACCTCCACAGCGGCTTCCTTGATCCTTGCCACCCGCGACTGAACACC
GACAGCAGCAGCCTCACCATGAAGTTGCTGATGGTCCTCATGCTGGCGGCCCTCTCCCAGCACTGCTACG
CAGGTGAGTTCTGTGCAGGGAGGGCTGCCTCGGGGTTAGGGGTTGTCACTTGGGCCTCTATGGAAGAACT
CCTGCTCCCCAATTCTCAGCAGAGATCAGCCCCAGTACAAAGGCTGTAGGTATAACAGATCTCACCATGT
TGCCCAGGCTGGTCTTGAACTCCTGAGCTCAGGCAGTCTGTCCACCTCGGCCTCCCAAAGTGCTGGGATT
ATAGGTGTGAGCCACCACACTTGGCCTAAGATACTTGGAAATCTTCTGTGATGCTCTGAATGGTAATAGT
GAAGCATCGTATGATTTTGAACCAAAGAAGACCAAATAATCTTCACGATATACTTCCAAGTCCGAGTGTT
TCATTTCTCAAGTCTTCTCATTAAATGAAGTTTCATGAGGTTTAGCTTTTCTGGGCTGGGGAGTGGAGAG
AAAGAAGTTGCAGGGCTTACAGGAAATCCCAGAGCCTGAGGTTTTCTCCCAGATTTGAGAACTCTAGATT
CTGCATCATTATCTTTGAGTCTATATTCTCTTGGGCTGTAAGAAGATGAGGAATGTAATAGGTCTGCCCC
AAGCCTTTCATGCCTTCTGTACCAAGCTTGTTTCCTTGTGCATCCTTCCCAGGCTCTGGCTGCCCCTTAT
TGGAGAATGTGATTTCCAAGACAATCAATCCACAAGTGTCTAAGACTGAATACAAAGAACTTCTTCAAGA
GTTCATAGACGACAATGCCACTACAAATGCCATAGATGAATTGAAGGAATGTTTTCTTAACCAAACGGAT
GAAACTCTGAGCAATGTTGAGGTGTTTATGGTAATTTCATTTTCTTCCTATAAGCTTTTTAAATCCCCTG
ACCAGGGACAAGTGGGCTCTTCATTTCTCACTGACAATGCCAAAGCCACTAGTGAACAAGCCTTTTCTTA
CATTGGTTAATTTAGTTGAATGGTTAGTCTAATGACTTTGCCATCAAGAAAAACATCCAGTGTCCCTGTG
TTGTCACTCTACCCAGAGAATCCTCAGTGGATGATAAATGAATAGGGCAAGAGAGGAAAAGGAAAGGTCG
GTAGAAGTCTTACCTATCCCCAGAGCTCTCTAATTCATGCTCACAAACACAGACACAATCACACAAACAC
AGAAACACACATACACACATCCAGACACATGCAAACACACAGACACAGTCACAATCACACAAACACACAC
ACATTCAGACATACACAAACATAGACAGACAGGCAAAGACACAGACACAGACACAGACACAATCACACCA
GCACACAATCATCCAGACACAAACACAAACACACAGACAGAACCACACAACCACAGAAACACAGAGACAC
ACACAAACACACTCAGACACACACATACAAACATATGTTCACTCTCTACAGAAAAAACAATTTTCCAGAA
GACCCGCACCTATAGACCAATCTGCAGAGAAAACTTCTCTTCTTCAAAAAAAAGTAAAAGTGTTCTTTCT
TAAAAAATGCCCTATTTTTCAACAGTTTGGAAAATACCATTTGAGCAAGATTCTATACATCTCAAATAAA
AAGAATTTAAAATGCACTTCCAGGCAATCATAATTTGCTAGCATAAATGATGAGAAACCTTGGACTATCC
AATAGGCAACTGTAGATCATGGGTATGAAACCACCATGGAGGAAGAATTGCCTCAAACAAAAACCAATAG
TTTTGTATTTCTTTCTAACTATACATGTATATTGTTGAGGGTTTTCTTTAGCATTTATTCCCTATGTTAA
ATTCTTCTTTAATCCTTCCCTGGTAAAAAAAAAAAAAAAAAAAAAGTTAGAAATATACCAAACCCCTCCA
TTAGGATGAAAGTGAACATCACCTCAGGAAACCCTGACGCTTTCTACAACATGGATGAACCTTGAGGATA
TTATAGCGAGTGAAGAGTGAAGCAAAGAGTCACAAAAACACAAATGCTGCATGACCCATGCATATGGGAA
TCTGGGGAGCCAGACTCAGAGACAGTGAAAAAAAAAAAAACAGTGGTTGTCAGGGCTTGGGTGCAGAGAA
GAAGGGGGAGTCATATTTAATGGGTCTGGAGTTTCAGTTGTGCAAAACAGTAATATTCTGGAGTTAGGTT
GCACAACCACACGAATATACAGAACACTCCGAACTGTCCCCTTAAAATGGCAAATTTTATGAGATGTACA
TTTTACCACTATTAATAATTTGTTAAAAACTAATTATCAACTGCAGGGAAGGGTGATGGATTTGTTTCTT
TAAAAGCTTCCTCAGACAGATCATAGTCTGCAGCTCCAATAATTAGTAGAGCACAATGGTGGTGGCAGAG
GGCGTCGGACTGCTGGGATGCTGGGAATATTTCCACAATGGAGGGTTAGACGAGAGCTCAAAGTTTCACT
TTTTTTTTTTTTTTTTTTTTTGCATTTGAGCTAAGATTTTAACAATCCTGTGAAAATAGGTAATATAGTC
ACGTATTTGTTGAATACATTATTTCAAAGAACCACAAACACACAGAAAAAATATTTAAAAAGTCCATGGT
GGGGGAAATGATCCAGAAACAACAGCTCTTCTACTTCCAGCCCTAACCGTCTGGGATGCTAGATGGTTGT
GGGCAAACCGTGGAAAAAGATAAGCTTCTGTTTTTCAAGATTTTATTTTGTTAGAGAGTGCAGAAAATCT
AAGTGATGTCTCTGTTTTTGCTTTCTAGCAATTAATATATGACAGCAGTCTTTGTGATTTATTTTAACTT
TCTGCAAGACCTTTGGCTCACAGAACTGCAGGGTATGGTGAGAAACCAACTACGGATTGCTGCAAACCAC
ACCTTCTCTTTCTTATGTCTTTTTACTACAAACTACAAGACAATTGTTGAAACCTGCTATACATGTTTAT
TTTAATAAATTGATGGCAAAA
Protein Information
Protein Name transcript variant X1
NCBI Protein GI 4505169
Protein Accession NP_002402
Protein pI 3.93
Protein Weight 10002.61
Protein Length 93
Protein Sequence 
>NP_002402.1 mammaglobin-A precursor [Homo sapiens]
MKLLMVLMLAALSQHCYAGSGCPLLENVISKTINPQVSKTEYKELLQEFIDDNATTNAIDELKECFLNQT
DETLSNVEVFMQLIYDSSLCDLF
Epitope Information
IEDB Linear Epitope