VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (28)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


LpnA

General Information
Protegen ID 477
Sequence Strain (Species/Organism) Francisella tularensis subsp. tularensis SCHU S4
VO ID VO_0011079
Taxonomy ID 177416
Molecule Role Protective antigen
Molecule Role Annotation Anti-lpnA MAbs conferred significant, although not complete, protection of naïve C3H/HeN mice from lethal challenge with F. tularensis LVS when administered therapeutically (Savitt et al., 2009).
References
Savitt et al., 2009: Savitt AG, Mena-Taboada P, Monsalve G, Benach JL. Francisella tularensis infection-derived monoclonal antibodies provide detection, protection, and therapy. Clinical and vaccine immunology : CVI. 2009; 16(3); 414-422. [PubMed: 19176692].
Gene Information
Gene Name LpnA
NCBI Gene ID 3191792
Genbank Accession AJ749949
Locus Tag FTT_0901
Gene Starting Position 909953
Gene Ending Position 910402
DNA Sequence 
>NC_006570.2:909953-910402 Francisella tularensis subsp. tularensis SCHU S4 chromosome, complete genome
TATGAAAAAAATAATTGAGCTTAGTCTTTTATCTTTATCAATCGCAGGTTTAGCGAGCTGTTCTACTCTA
GGGTTAGGTGGCTCTGATGATGCAAAAGCTTCAGCTAAAGATACTGCTGCTGCTCAGACAGCTACTACTG
AGCAAGCTGCTGCTGTATCTAAGCCAACTGCAAAAGTAAGTTTAAATAAACTTGGTCAGGATAAAATAAA
AGCAACTGTATATACAACATACAATAATAACCCACAAGGAAGTGTAAGATTACAATGGCAGGCTCCAGAA
GGTTCTAAGTGCCATGATACAAGCTTCCCAATTACTAAGTATGCTGAGAAGAACGATAAAACTTGGGCAA
CTGTAACAGTTAAGCAAGGTAATAACTTCTGTAGCGGTAAGTGGACAGCTAATGTAGTTTATGACAAAGA
AGTAATCGCTTCTGATTCAATAAATATTTA
Protein Information
Protein Name lipoprotein
NCBI Protein GI 56708002
Protein Accession YP_169898
Protein pI 9.16
Protein Weight 14909.46
Protein Length 149
Protein Note Paralog to conserved hypothetical lipoprotein lpnB.
Protein Sequence 
>YP_169898.1 lipoprotein [Francisella tularensis subsp. tularensis SCHU S4]
MKKIIELSLLSLSIAGLASCSTLGLGGSDDAKASAKDTAAAQTATTEQAAAVSKPTAKVSLNKLGQDKIK
ATVYTTYNNNPQGSVRLQWQAPEGSKCHDTSFPITKYAEKNDKTWATVTVKQGNNFCSGKWTANVVYDKE
VIASDSINI
Epitope Information
IEDB Linear Epitope