VIOLIN: Vaccine Investigation and Online Information Network

E0

General Information

Protegen ID

443

VO ID

VO_0010898

Taxonomy ID

11096

Other Database IDs

CDD:294141
CDD:238220

Molecule Role

Protective antigen

Molecule Role Annotation

Swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever (König et al., 1995).

Related Vaccines(s)

Classical swine fever virus vaccine VAC-E0 , rPFV-CSFV-E0

References

KÃ¶nig et al., 1995: KÃ¶nig M, Lengsfeld T, Pauly T, Stark R, Thiel HJ. Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins. Journal of virology. 1995; 69(10); 6479-6486. [PubMed: 7666549].

Gene Information

Gene Name

Protein Information

Protein Name

envelope glycoprotein E0

NCBI Protein GI

115343287

Protein pI

7.85

Protein Weight

25600.45

Protein Length

313

Protein Note

Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf...; cl00208

Protein Sequence

>ABI94604.1 envelope glycoprotein E0, partial [Classical swine fever virus]
ENITQWNLSDNGTNGIQRAMYLRGVNRSLHGIWPEKICKGVPTHLATDTELTEIRGMMDASERTNYTCCR
LQRHEWNKHGWCNWYNVDPWIQLMNRTQANLTEGPSDKECAVTCRYDRNADVNVVTQARNRPTTLTGCRK
GKNFSFAGTVIEGPCNFNVSVEDILYGDHECGSLLQDTALYLLDGMTNTIENARQGAARVTSWLGRQLST
AGKKLERRSKTWFGAYALSPYC

Epitope Information

IEDB Linear Epitope