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PI1

General Information
Protegen ID 4346
Sequence Strain (Species/Organism) Toxoplasma gondii
Taxonomy ID 5811
Other Database IDs CDD:238052
Molecule Role Protective antigen
Molecule Role Annotation (Picchio et al., 2018)
References
Picchio et al., 2018: Picchio MS, Sánchez VR, Arcon N, Soto AS, Perrone Sibilia M, Aldirico MLA, Urrutia M, Moretta R, Fenoy IM, Goldman A, Martin V. Vaccine potential of antigen cocktails composed of recombinant Toxoplasma gondii TgPI-1, ROP2 and GRA4 proteins against chronic toxoplasmosis in C3H mice. Experimental parasitology. 2018; 185; 62-70. [PubMed: 29309783].
Gene Information
Gene Name PI1
NCBI Gene ID 7901030
Protein Information
Protein Name serine protease inhibitor 1 isoform beta
NCBI Protein GI ADJ17341
Protein pI 4.61
Protein Weight 30858.24
Protein Length 373
Protein Note Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Protein Sequence
>ADJ17341.1 serine protease inhibitor 1 isoform beta [Toxoplasma gondii]
MGKNPLLFLAGVLVCSFSVAVFASPETKVCSCPRNLELNCGGDHVTYANHCIRECHGVGLLHDGPCADQE
DQGSSVNEPSEVADTTEQPSITPSGEEDRPPKDAPKERKRLRGCACTRELRLNCGVDGVTYSNHCVRKCE
RVKLLHEGPCRGGPGRTLFSQQDDESENDALEEEEQRLQSCPCPLNLMLNCGVDGVTYDNHCLRRCRRVE
LKHEGPCEADEQKQLPVQHGDNEIDVPERRIEDLKDCACPLILTPNCGTDRKTYPNNCVRECAGVKLLHE
GPCEGDTEEIWDDQ

Epitope Information
IEDB Linear Epitope