VIOLIN: Vaccine Investigation and Online Information Network

E2 protein

General Information

Protegen ID

4335

Sequence Strain (Species/Organism)

chikungunya virus

Taxonomy ID

37124

Other Database IDs

CDD:279311

Molecule Role

Protective antigen

Molecule Role Annotation

(Lam et al., 2015)

Related Vaccines(s)

MV-CHIK Vaccine

References

Lam et al., 2015: Lam S, Nyo M, Phuektes P, Yew CW, Tan YJ, Chu JJ. A potent neutralizing IgM mAb targeting the N218 epitope on E2 protein protects against Chikungunya virus pathogenesis. mAbs. 2015; 7(6); 1178-1194. [PubMed: 26305993].

Gene Information

Gene Name

E2 protein

Protein Information

Protein Name

E2 protein

NCBI Protein GI

AEJ18140

Protein pI

7.78

Protein Weight

44672.18

Protein Length

483

Protein Note

Alphavirus E2 glycoprotein; pfam00943

Protein Sequence

>AEJ18140.1 E2 protein, partial [Chikungunya virus]
STKDNFNVYKATRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIKTDDSHDWTKLRYM
DNHMPADAERAGLFVRTLAPCTITGTMGHFILARCPKGETLTVGFTDSRKISHSCTHPFHHDPPVIGREK
FHSRPQHGKELPCSTYVQSTAATTEEIEVHMPPDTPDHTLMSQQSGNVKITVNGQTVRYKCNCGGSNEGL
TTTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKIHIPFPLANVTCRVPKARNPTVTYGK
NQVIMLLYPDHPTLLSYRNMGEEPNYQEEWVMHKKEVVLTVPTEGLEVTWGNNEPYKYWPQLSTNGTAHG
HPHEIILYYYELYPTMTVVVVSVATFILLSMVGMAAGMCMCARRRCITPYELTPGATVPFLLSLICCIRT
AKA

Epitope Information

IEDB Linear Epitope