VIOLIN: Vaccine Investigation and Online Information Network

E

General Information

Protegen ID

4276

Sequence Strain (Species/Organism)

Tick-borne Encephalitis Virus (TBEV)

Taxonomy ID

11084

Other Database IDs

CDD:279241
CDD:213392
CDD:213897
GOA:Q8UYS5
HSSP: 1SVB
InterPro: IPR000336
InterPro: IPR011998
InterPro: IPR011999
InterPro: IPR013755
InterPro: IPR013756
InterPro: IPR014756
UniProtKB/TrEMBL: Q8UYS5

Molecule Role

Protective antigen

Molecule Role Annotation

(Stenkova et al., 2017)

Related Vaccines(s)

Encepur

References

Stenkova et al., 2017: Stenkova AM, Chopenko NS, Davydova LA, Mazeika AN, Bystritskaya EP, Portnyagina OY, Anastyuk SD, Kulbatskii DS, Lyukmanova EN, Dolgikh DA, Kostetsky EY, Sanina NM. Engineering of Chimeric Protein Based on E Protein Domain III of Tick- Borne Encephalitis Virus and OmpF Porin of Yersinia pseudotuberculosis. Protein and peptide letters. 2017; 24(10); 974-981. [PubMed: 28741465].

Gene Information

Gene Name

Protein Information

Protein Name

E protein

NCBI Protein GI

CAC94472

Protein pI

7.56

Protein Weight

42769

Protein Length

494

Protein Note

Flavivirus glycoprotein, central and dimerization domains; pfam00869

Protein Sequence

>CAC94472.1 E protein, partial [Tick-borne encephalitis virus]
TQGTTRVTLVLELGGCVTITAEGKPSMDVWLDSIYQENPAKTREYCLHAKLSDTKVAARCPTMGPAVLAE
EHQSGTVCKRDQSDRGWGNHCGLFGKGSIVTCVKAACEAKKKATGHVYDANKIVYTVKVEPHTGDYVAAN
ETHSGRKTASFTVSSEKTILNMGDYGDVSLLCRVASGVDLAQTVILELDKTLEHLPTAWQVHRDWFNDLA
LPWKHEGAQHWNNAERLVEFGAPHAVKMDVYNLGDQTGVLLKSLAGVPVAHIDGTKYHLKSGHVTCEVGL
EKLKMKGLTYTMCDKTKFTWKRTPTDSGHDTVVMEVTFSGTKPCRIPVRAVAHGSPDVNVAMLITPNPTI
ENNGGGFIEMQLPPGDNIIYVGELSHQWFQKGSSIGRVFQKTRKGIERLTVIGEHAWDFGSTGGFLTSVG
KAL

Epitope Information

IEDB Linear Epitope