VIOLIN: Vaccine Investigation and Online Information Network

emm12 mutant

General Information

Protegen ID

4112

Sequence Strain (Species/Organism)

Streptococcus pyogenes

Taxonomy ID

1314

Other Database IDs

ATCC:12353
CDD:273479
CDD:302792
CDD:303051
CDD:287450
CDD:295219

Molecule Role

Protective antigen

Molecule Role Annotation

(McNeil et al., 2005)

References

McNeil et al., 2005: McNeil SA, Halperin SA, Langley JM, Smith B, Warren A, Sharratt GP, Baxendale DM, Reddish MA, Hu MC, Stroop SD, Linden J, Fries LF, Vink PE, Dale JB. Safety and immunogenicity of 26-valent group a streptococcus vaccine in healthy adult volunteers. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2005; 41(8); 1114-1122. [PubMed: 16163629].

Gene Information

Gene Name

emm12 mutant

Protein Information

Protein Name

M12 mutant protein precursor

NCBI Protein GI

BAD14986

Protein pI

8.53

Protein Weight

55130.42

Protein Length

583

Protein Note

Gram-positive signal peptide, YSIRK family; TIGR01168

Protein Sequence

>BAD14986.1 M12 mutant protein precursor [Streptococcus pyogenes]
MAKNTTNRHYSLRKLKTGTASVAVALTVVGAGLVAGQTVRADHSDLVAEKQRLEDLGQKFERLKQRSELY
LQQYYDNKSNGYKGDWYVQQLKMLNRDLEQAYNELSGEAHKDALGKLGIDNADLKAKITELEKSVEEKND
VLSQIKKELEEAEKDIQFGREVHAADLLRHKQEIAEKENVISKLNGELQPLKQKVDETDRNLQQEKQKVL
SLEQQLAVTKENAKKDFELAALGHQLADKEYNAKIAELESKLADAKKDFELAALGHQHAHNEYQAKLAEK
DGQIKQLEEQKQILDASRKGTARDLEAVRQAKKATEAELNNLKAELAKVTEQKQILDASRKGTARDLEAV
RKAKAQVEAALKQLEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGL
RRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEE
LAKLRAGVAAVVKRKEEN

Epitope Information

IEDB Linear Epitope