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omlA

General Information
Protegen ID 4095
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 2 str. S1536
Taxonomy ID 871925
Other Database IDs CDD:295696
GOA:O31239
InterPro: IPR001677
UniProtKB/TrEMBL: O31239
Molecule Role Protective antigen
Molecule Role Annotation CpxD) as well as surface antigens TbpA, TbpB, and OmlA. These data identify OM proteins that demonstrate immunogenicity and upregulation under conditions mimicking infection, providing emphasis on lipoproteins as an important class of antigens to exploit for vaccine development for A. pleuropneumoniae.(Chung et al., 2012)
References
Chung et al., 2012: Chung JW, Küster-Schöck E, Gibbs BF, Jacques M, Coulton JW. Immunoproteomic analyses of outer membrane antigens of Actinobacillus pleuropneumoniae grown under iron-restricted conditions. Veterinary microbiology. 2012; 159(1-2); 187-194. [PubMed: 22541161].
Gene Information
Gene Name omlA
Protein Information
Protein Name OmlA
NCBI Protein GI CAA73336
Protein pI 7.48
Protein Weight 23674.62
Protein Length 306
Protein Note Transferrin binding protein-like solute binding protein; cl03152
Protein Sequence
>CAA73336.1 omlA, partial [Actinobacillus pleuropneumoniae serovar 2 str. S1536]
KDINSGIINNADVVLNLKIDEKDQIKIVLDKSEINRDSLKVTNAIPTQDIKTLKDSSGKLLGYYGYMQLS
QVRQDESYSTDSLNLSNYYLLSMNEQEKTRPSKSLTYKGTMIYGYSSVANNKLEAEVKAQYDHSSKKLSM
QVFGQDNEHWRLAEASGINNVKLPASKLRDVIVSDKGDINGLLYLEDSTPSKFTPNANFSGGFFGKNGEV
LAGKAESIKG

Epitope Information
IEDB Linear Epitope