VIOLIN: Vaccine Investigation and Online Information Network

oppA

General Information

Protegen ID

4075

Sequence Strain (Species/Organism)

Burkholderia pseudomallei

Taxonomy ID

28450

Molecule Role

Protective antigen

Molecule Role Annotation

(Tippayawat et al., 2009)

References

Tippayawat et al., 2009: Tippayawat P, Saenwongsa W, Mahawantung J, Suwannasaen D, Chetchotisakd P, Limmathurotsakul D, Peacock SJ, Felgner PL, Atkins HS, Titball RW, Bancroft GJ, Lertmemongkolchai G. Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei. PLoS neglected tropical diseases. 2009; 3(4); e407. [PubMed: 19352426].

Gene Information

Gene Name

oppA

Protein Information

Protein Name

oligopeptide ABC transporter periplasmic oligopeptide-binding protein

NCBI Protein GI

CRY20041

Protein pI

8.97

Protein Weight

56354.83

Protein Length

658

Protein Sequence

>CRY20041.1 oligopeptide ABC transporter periplasmic oligopeptide-binding protein [Burkholderia pseudomallei]
MKHTHAFAAVLAALALTIAPSAPAVTVASNVTLADQQDLTRQVPAEVESLDPAHIESWTGNTIGLDLFEG
LARIDASGAVVPGVAQAWEHKAPDTWIFKLRRDAKWSNGQPVTAADFVYAWQRLADPKTGSKYTILVEFV
KNASAIIAGKQPPGDLGIRAIDPYTIEVKTEVPVSYFPELTAMAPLTPVNKDAVAKFGDAWTRPKNIVSN
GPYTLVDWQPNNRIVMAKSDKYWNARNVVIRKVTYLPIENDETALRMYQAGQIDYTYSIPAGGFGQISKQ
FGKELRPGLQLATYYYYLKNSDPALKDKRVREALAMVLDREILTSKITQAGEVPMYGLMPKGVKGVQRPF
TPDWASWPMARRVDYAKNLLKQAGHGDANPLTFTLTYNTNDLHKKVALFAASEWRTKLGVTAKLENVEFK
VLMKQRHDGKVQVARDGWFADYNDAMTFFDLIRCGSSQNTVGYCNPKVDSLVAEANQKLDDGARAALLTQ
AHDLAMNDYPMVPLFQYSADRLVKSYVGGYTLTNYIDMRASQDMYLIKH

Epitope Information

IEDB Linear Epitope

IEDB ID	Epitope	MHC restriction	Starting position	Ending position
192910	DPKTGSKYTILVEFVKNASA	HLA-DRB1*01:01	126	146
193037	PKVDSLVAEANQKLDDGARA	HLA-DRB101:01 HLA-DQB103:02	466	486
193128	YVGGYTLTNYIDMRASQDMYLIKH	HLA-DRB101:01 HLA-DRB115:02 HLA-DQB1*03:02	516	540
242211	YYLKNSDPALKDKRVREALA		296	316
241605	ALLTQAHDLAMNDYPMVPLF		486	506
241673	DLFEGLARIDASGAVVPGVA		66	86
242147	TYSIPAGGFGQISKQFGKEL		266	286
242188	WIFKLRRDAKWSNGQPVTAA	HLA-DRB1*15:02	96	116
242191	WSNGQPVTAADFVYAWQRLA		106	126
242143	TVASNVTLADQQDLTRQVPA		26	46
242146	TYNTNDLHKKVALFAASEWR		386	406
242158	VDWQPNNRIVMAKSDKYWNA		216	236
242176	VQRPFTPDWASWPMARRVDY		346	366
242150	VALFAASEWRTKLGVTAKLE		396	416
242193	YFPELTAMAPLTPVNKDAVA		176	196
242020	QYSADRLVKSYVGGYTLTNY	HLA-DQB1*03:02	506	526
242095	SSQNTVGYCNPKVDSLVAEA		456	476
242041	RNVVIRKVTYLPIENDETAL		236	256
242043	RPGLQLATYYYYLKNSDPAL	HLA-DQB1*03:02	286	306
242102	SWPMARRVDYAKNLLKQAGH		356	376
242119	TKLGVTAKLENVEFKVLMKQ		406	426
242002	QAWEHKAPDTWIFKLRRDAK	HLA-DRB1*15:02	86	106
242004	QISKQFGKELRPGLQLATYY		276	296
242039	RMYQAGQIDYTYSIPAGGFG	HLA-DQB1*03:02	256	276
241970	NIVSNGPYTLVDWQPNNRIV		206	226
241975	NQKLDDGARAALLTQAHDLA		476	496
242197	YGLMPKGVKGVQRPFTPDWA		336	356
241962	MTFFDLIRCGSSQNTVGYCN		446	466
241964	MVLDREILTSKITQAGEVPM		316	336
241931	LTPVNKDAVAKFGDAWTRPK		186	206
241935	LVEFVKNASAIIAGKQPPGD		136	156
241942	MAKSDKYWNARNVVIRKVTY		226	246
241947	MNDYPMVPLFQYSADRLVKS		496	516
241847	KITQAGEVPMYGLMPKGVKG		326	346
241894	LGIRAIDPYTIEVKTEVPVS		156	176
241913	LPIENDETALRMYQAGQIDY		246	266
241930	LTIAPSAPAVTVASNVTLAD		16	36
241751	GDANPLTFTLTYNTNDLHKK		376	396
241811	IEVKTEVPVSYFPELTAMAP		166	186
241842	KDKRVREALAMVLDREILTS		306	326
241845	KFGDAWTRPKNIVSNGPYTL		196	216
241726	ESWTGNTIGLDLFEGLARID	HLA-DQB1*03:02	56	76
241628	ASGAVVPGVAQAWEHKAPDT	HLA-DQB1*03:02	76	96
241667	DFVYAWQRLADPKTGSKYTI		116	136
241727	EVESLDPAHIESWTGNTIGL	HLA-DQB1*03:02	46	66
242011	QQDLTRQVPAEVESLDPAHI	HLA-DQB1*03:02	36	56
241587	AFAAVLAALALTIAPSAPAV		6	26
241601	AKNLLKQAGHGDANPLTFTL		366	386