In intranasal challenge assays of mice, immunization with ETEC_2479 protected 88% of mice from an otherwise lethal challenge with ETEC H10407. Immunization with MipA provided an intermediate degree of protection of 64% (Kumar et al., 2015)
References
Kumar et al., 2015: Kumar A, Hays M, Lim F, Foster LJ, Zhou M, Zhu G, Miesner T, Hardwidge PR. Protective Enterotoxigenic Escherichia coli Antigens in a Murine Intranasal Challenge Model. PLoS neglected tropical diseases. 2015; 9(8); e0003924. [PubMed: 26244636].
