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UL49

General Information
Protegen ID 389
Sequence Strain (Species/Organism) Bovine alphaherpesvirus 1
VO ID VO_0011040
Taxonomy ID 10320
Molecule Role Protective antigen
Molecule Role Annotation Protection against a BHV-1 challenge was obtained in calves immunized with the plasmid encoding tgD-VP22 (UL49), as shown by significant reductions in viral excretion (Zheng et al., 2005).
Related Vaccines(s) Bovine herpesvirus 1 DNA vaccine tgD-VP22
References
Zheng et al., 2005: Zheng C, Babiuk LA, van Drunen Littel-van den Hurk S. Bovine herpesvirus 1 VP22 enhances the efficacy of a DNA vaccine in cattle. Journal of virology. 2005; 79(3); 1948-1953. [PubMed: 15650221].
Gene Information
Gene Name UL49
NCBI Gene ID 1487397
Genbank Accession GU591892
Locus Tag BoHV1_gp05
Gene Starting Position 9383
Gene Ending Position 10228
DNA Sequence 
>NC_001847.1:9383-10228 Bovine herpesvirus 1, complete genome
CATGGCCCGGTTCCACAGGCCCTCCGAAGACGAGGACGATTACGAGTACAGCGACCTTTGGGTGCGAGAA
AACAGCCTCTATGACTACGAGTCCGGCTCGGATGACCACGTATACGAAGAGCTGCGCGCCGCGACGAGCG
GACCCGAGCCGAGCGGGCGGCGCGCTAGCGTCCGTGCGTGCGCCAGCGCTGCAGCCGTCCAGCCCGCCGC
CCGCGGCCGCGATCGAGCCGCAGCCGCGGGGACGACCGTAGCTGCGCCCGCCGCCGCGCCGGCCCGCCGC
TCGAGCAGCCGGGCGTCCTCGCGCCCGCCGCGAGCTGCCGCCGACCCGCCCGTCCTCCGGCCAGCCACGC
GCGGGTCCTCCGGCGGCGCCGGGGCAGTCGCCGTCGGTCCACCTCGACCTCGCGCGCCCCCCGGTGCTAA
TGCTGTTGCGTCTGGCCGGCCGCTGGCGTTCAGCGCGGCTCCGAAAACGCCCAAGGCGCCCTGGTGTGGA
CCGACGCACGCCTACAACCGAACGATCTTTTGCGAGGCCGTCGCGCTCGTGGCCGCCGAGTACGCCCGGC
AGGCGGCTGCCAGCGTCTGGGACTCGGACCCCCCAAAGAGCAACGAGCGATTGGATCGCATGTTGAAGTC
GGCGGCAATTCGCATCCTCGTGTGCGAGGGCTCCGGGCTTCTCGCCGCCGCGAACGACATCTTGGCCGCG
CGGGCCCAGCGCCCCGCCGCGCGCGGGAGCACAAGCGGCGGGGAAAGCCGCCTTCGCGGCGAGCGGGCCC
GGCCGTAGCGCGAGCGGGAGGGCTTTTTCGACGCGCGCGGCTTAAGCAGCGCGCTGCTGTGCTAGTATGA
AAATAA
Protein Information
Protein Name tegument protein VP22
NCBI Protein GI 9629826
Protein Accession NP_045310
Protein pI 10.07
Protein Weight 25574.19
Protein Length 258
Protein Sequence 
>NP_045310.1 tegument protein VP22 [Bovine alphaherpesvirus 1]
MARFHRPSEDEDDYEYSDLWVRENSLYDYESGSDDHVYEELRAATSGPEPSGRRASVRACASAAAVQPAA
RGRDRAAAAGTTVAAPAAAPARRSSSRASSRPPRAAADPPVLRPATRGSSGGAGAVAVGPPRPRAPPGAN
AVASGRPLAFSAAPKTPKAPWCGPTHAYNRTIFCEAVALVAAEYARQAAASVWDSDPPKSNERLDRMLKS
AAIRILVCEGSGLLAAANDILAARAQRPAARGSTSGGESRLRGERARP
Epitope Information
IEDB Linear Epitope