VIOLIN: Vaccine Investigation and Online Information Network

algE

General Information

Protegen ID

3884

Sequence Strain (Species/Organism)

Pseudomonas aeruginosa

Taxonomy ID

208964

Other Database IDs

CDD:315937

Molecule Role

Protective antigen

Molecule Role Annotation

Furthermore, we suggest to include AlgE in a multicomponent experimental vaccine for potential protection of non-colonized CF patients from colonization with mucoid P. aeruginosa.(Rehm et al., 1994)

References

Rehm et al., 1994: Rehm BH, Grabert E, Hein J, Winkler UK. Antibody response of rabbits and cystic fibrosis patients to an alginate-specific outer membrane protein of a mucoid strain of Pseudomonas aeruginosa. Microbial pathogenesis. 1994; 16(1); 43-51. [PubMed: 8057826].

Gene Information

Gene Name

algE

Protein Information

Protein Name

alginate production protein AlgE

NCBI Protein GI

NP_252234

Protein pI

4.64

Protein Weight

53211.29

Protein Length

574

Protein Note

Alginate export; pfam13372

Protein Sequence

>NP_252234.1 alginate production protein AlgE [Pseudomonas aeruginosa PAO1]
MNSSRSVNPRPSFAPRALSLAIALLLGAPAFAANSGEAPKNFGLDVKITGESENDRDLGTAPGGTLNDIG
IDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTDDGNNSRNDGREPDKSYLAAREFWVDYAGLTA
YPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGD
ISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATW
LTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLE
SNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQ
PGEKDIGQELDLVVTKYFKQGLLPASMSQYVDEPSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF

Epitope Information

IEDB Linear Epitope