VIOLIN: Vaccine Investigation and Online Information Network

Cd40lg

General Information

Protegen ID

305

Sequence Strain (Species/Organism)

Mus musculus

Taxonomy ID

10090

Molecule Role

Protective antigen

Molecule Role Annotation

Transgenic expression of the CD40L (Cd40lg) increased immune responses against a weakly immunogenic murine tumor, neuro-2a.Tumor cells were transduced with a retroviral construct containing the CD40L gene and co-injected with variable numbers of non-CD40L transduced cells into syngeneic mice. Mice injected with cells that expressed CD40L had a significant reduction in average tumor size as compared to controls (p < 0.0001). In addition, survival of the neuro-2a/CD40L mice was 48 days versus 34 days for the neuro-2a/neo controls (p < 0.02). Expression of CD40L by less than 1.5% of neuro-2a cells was sufficient for significant antitumor effects (p < 0.001). These antitumor effects protected mice from subsequent challenge with parental neuro-2a cells (Grossmann et al., 1997).

Related Vaccines(s)

Cancer Retroviral Vector Vaccine encoding Cd40lg

References

Grossmann et al., 1997: Grossmann ME, Brown MP, Brenner MK. Antitumor responses induced by transgenic expression of CD40 ligand. Human gene therapy. 1997; 8(16); 1935-1943. [PubMed: 9382959].

Gene Information

Gene Name

Cd40lg

NCBI Gene ID

21947

Genbank Accession

AH006031

Chromosome No

Locus Tag

RP23-153G22.3

Gene Starting Position

57212142

Gene Ending Position

57224041

DNA Sequence

>NC_000086.7:57212142-57224041 Mus musculus strain C57BL/6J chromosome X, GRCm38.p4 C57BL/6J
GCTTTCAGTCAGCATGATAGAAACATACAGCCAACCTTCCCCCAGATCCGTGGCAACTGGACTTCCAGCG
AGCATGAAGATTTTTATGTATTTACTTACTGTTTTCCTTATCACCCAAATGATTGGATCTGTGCTTTTTG
CTGTGTATCTTCATAGAAGATTGGATAAGGTAAGGTGACCTACAAGCCTTAATTAGCTAAATTGGGGGTT
CTTATTGATCTAGGACGGTTTGAATTAAGTTCTACCTAAATGATGGAGAACAGTAGAAAGTGGATAATGT
TTGTTGTGGCATAATGTTTGTTGCCTAGAAAGTAGAACCTTACCTCTGACTAAGATCTTGGAATGTGCAA
TCAGACAGCCTGGCTTCAAATCTTAGCTTAGCTCTTAACTGCTCTGAGATTCTGCACATGTCACTTCATA
TTTTCATTTCTTTTTCTGTCCCAGGGAAATAGAGGTAGACATAGTACCCATGGCACAGATCAAATGATTC
TAGCCCTGAAGAGGAGATAAACTATGCCTGGCACATAGTACATGCTAGTTAGTTCCTAAAAGTTGCTCCC
CAAAGTGAACTATTTCCCCCCACGAAGACAACTTTAAAAAAATGAGCCCCATGAAAACAACTTTAAAAGG
TGAGCCAGAAAAAAAGGAACATTGATTTGATCTGAAATTCCATTGTGTTTTGGATGAGTACAGACATGAA
CTATGCTCCCAATCTGCCGATTGATTTTTAAAGTCAGAATGGTGCTATCTGTGCAACTCTTCAATGCCAA
CTGCCACTGTAAGCTGCTCTGTGCTCCGCGGAGGAGATTTTCCATGCTTAAATGATTAGGAAGGGAGCAG
ACTAGCTAAGAACAGTAACTTCAGGATCTACGCTGTTTCCATGTGCTGGCTCATATCCACTGAGGGCCAT
ATGGGCTGTGTTATGAAATGCTAAGGGATAATGGGGAAGTTGTAACCCATATAGACTCAAATGTGCTGTC
AAATTTAAGTGAACTTTAAATGACAGGCAAAGCTATTGGCAAACTCCACCTTATATTTTGTTTTGATTTT
ATTTGGTTAAGTTTGGATTTTTCCCCCCTTTTTGAGACAGTTTCATACTGTAGCTCAGAATGGTCTGGAA
CTCTCTAGATAGACGAAACTGGCTTCTAACTCACAGGAACACTCCTGCCTCATCCTACAAATATAGAGAT
TACACACATGTTCCACTATACTTGTATTGGTTCTTGTTTTGAAAGTTAAGAATTTGCCCTTAAGACAAGA
AGAAATTGTTCAGAATTAGTTGACAACACAAGTTAATTGCATACATTTAATTACTCACATATAAAAAAGA
AAATATTGCATTCACTTTGGGGATAAGAGATAATTTCTTTTAAAATGCAAAGCATTTCTACAAGTACAGA
AGAAATGAGAGATGTAATTATAAATCCATGTTGTGAATGAATGCCGCTGTAATGCCTCGTGTCATGAACA
CTACCATGAAGCAGGCAAACTAGCTCGGCAGCAAACTACTTTATGGCTGGTGGGAAACATGACAATTATA
GGACACTGCTGTTGTGGTACACTGAGATTAAAAGTCATTAGAATAGCTATGATTTCTATTGAGAGGCACA
GAAAATATGCCATCGGAATCACCGGCTTTTTAGGCTGTTAAATGGCAAGTGCCAAACAGCAGTAATCCAG
CATGATACCTTTTAATATTCCCCCATTTACACTGTCAAAGTCCCCCTCTCGTCGGTGCCATGGAAGTGGA
TGTGGAGGCAGACGTGATTAGCTGCATTCTTCTTCACTATGACATTTCTCACCAGTCTCCTATTTCAAAA
CAGGTCGAAGAGGAAGTAAACCTTCATGAAGATTTTGTATTCATAAAAAAGCTAAAGAGATGCAACAAAG
GAGAAGGATCTTTATCCTTGCTGAACTGTGAGGAGATGAGAAGGCAATTTGAAGACCTTGTCAAGGTAAG
GTGCTCAGCTCCTGGCAGATTTCACAGAGAAGTTTTCTTACATTTCCCAGTCCTGCAAACTGAATTCTGA
CCCTGGGAAGCTTTAACGTATAAGCAGGGATAGTGGGCACAGCTGCGATCTCAGCGCCTGAGAGGCCAAA
GTCAAAGGACGACTGCTGTGGGTTCCAGGTCAGCTTGGTCTACAGAGTGAGACATGATCAAAATGTACTG
TATATAAACATACTCGTACATATATATACATGTACACACATATGTGTAGGTGTGGAAATGTGTACATACA
AAAAGAAAAGAAAAGACAAAGCCTTACAATAAAATGAAGAAGAGAGCTGAGTTGGCTATGTGCATACTAC
TGCAACAACAAAAAAGTTTTCATTCTTTTGTACAGATAATGTGTAATCCAATAATAGAGTAAAGAAGTCA
GGATCTTACTTCATTTATAAATTCATGACACATATGGAAGTCACAGGACAGCTTTCGAGTCTTGCTTCTT
TCCTTCCACTGTGTGAATCCTGCAGATTGAACTCACATCCTTAGGCTTAGCCTTTACCCACTGAGCCACT
TCATTGTTCTCTTCAAACCTTATTTCAGAACTTAATATACATCCTCCTATTTGGTCAGCAAGGTATAATT
TAACCTAGTGAAGAGGAAGATTCTAAAAACTTACTCCTAGGCCACTTACTGGGATCAGAATTCAGTTCAA
ATCTGCCTGACTTTATTTTAAGCTAGAATGTATTTTTTTTTAATTTTTCAAGACAATCTTGAGTAGCATA
GGATGGTCCTCAGCTTGTAGAAGACTTGTATGTGGCTGAAGACCTGCTCTCCACATCCTTCTGCTTCTAA
CCTCAGGCATGCAGCACTATGTCCAGTTTAATCTAGATTTTATTGTTTTAGTTTTGTACAATGCTCAGTT
GTTTGTACCTTGTGTATTAACCCTCCCCATTCTATAATCTAGGATTTCCATAAAATTCTTAACACTTTAT
TTGCAAGACTGGTGAGTTTAGAAAATGTCTTAGGTTTCTCCAGTGCTTACATGTAGAGTCCTAGGGACTG
AGACTCTATAAGGACACAACCAGCTCTGGTCTTCTCTCTGTGATCAGTCTTCAGTTTCTTTGAACGGCAG
TGAAAGTGGCTTGTTCTTTTTTTCCCTTTTCTCTCTGTTACAGAGAGGTTTCCCAGGTGACCTTCCAATT
CCCTTCATCCTCATTCAGGCCAGATGTAGAAAGCTTCCAGAATCATCTACCTAGGATAGGAGGGAAAGAG
TCTTTTCGGCTTTTATGAAAAAAAAAAAAAGTAGAACTTTTAAAGCTTATCAGCCAAGGCTGTAGGAGTG
TACTGTTTACCTGTCAGGGTATATAGAATTACTGTTTACCTGTCAGCTATGGAACTCCAAGCAATGCCAT
CTTTACCTAGGCTATAAAAAAGCTAAACTTCAAAGTTTTCCCATCAGCTAATTGTCCTCTATCTAAGGCT
CCCCCTTTAGGTCGCCATTTTCCTAGAGTTCTCGCTCAGAAACACAATTTGGAACTGTTGAGCCCAGCAA
GTCAACTGTAGACTAATTCCAGATTAGATTTGTGTTTTCTCAGCTAATGTGAGCAGACTTTGGACCATGA
GGTGGCTGGCCCAGAATAAACTTGAAGTCACGGGGCCTTCTGGGGTTTTAGAAACACTCCGGTGTAAATC
TCAATTCTTAGAATTCCAGTCTTCTCTTTACCATCTCTACAAAGTGGTCAGCCAATATTCATTTAAATAG
CTCTCATGACAAAGAGCACCTTAACTTCTGAGACAAGTATCATGGAGGTCTCATGGTGCATGGAAGATGG
GGGTCAGGGCTCGTGTTAGGGCAAATGCAGGCACCACTTTAAACAGTGTAATTACATAGTAAAATCTACT
TTGCTCCCGGTCTAGTATGGTCAGTCTCATGGTTATCTGTCTACCAGTTTCTGAAGTGTCTTTGATTGGC
ATCAAATCACTTCCATTTCAGGTTAAAGAGCTCATTATAACCTTATCTGCCATGTAGAATTTCCATGTAG
AGAGAAATCATTAATGTAAGATATTTATTTTTGAAATTTGACTTTAAAAACCCTTTCAATTGAAGTGAAG
AGTGAAGCCACACAAAAAAAGAAAAAAGGGCTCTGGGAGTGTGAGTTGGGGAAAGTTCACAAAAGTCAAG
GCTAGGTTCAGAAAAGACAAACTTTGCTGATTTCACGTTTTCATCTGGGCCAGGCCCCAACACCACTGCA
ACCACCTAGCCTAAACGTATCTCGACTTCAATCATCACACACTAGTGTTTGAAAAGCCACCAAAGAGTCC
TTTGTTTACTTGTCAGCTCGCAAACATTTTCCTGTTGCTGCATTGTCACGGTGCCCCCACCACAGCTCAA
ATGGAAAGTTGATCTGTGGGGCTCTCTGTGCTTTAAGCCCTCACTCACAGCTGGCAACCAAGCTGAGTCT
ATAGTTGCATTAGGCAAAAGTAACAACACAGACACCTTCTTGGGGTGAAGAATGTGAAGGAAAGGCCCAC
AATGCATTAGGTTCCAGGACTGAAAAGGAGCATAAGACTATCAGATCTGAAAGCACTGTTTTTTTTCCCT
GCCTGTTCTGAAGAGAGTGATGTAACAGATTGAGCCAGGTCTGTGAATTCTACTTTCTGTACTTCGTGTA
AGCCTCGGGCCCTTGGTTGATCTCATACTCACCAGGCCTTTGATTCAGACTTCTTAAAATGGCGGCAACA
GCCTTGATCATCTCTCGGGCTCCATAGAAGGAAGTCTGTGCTAGCTTCCTCAAGTATGTCCAGCATTCTT
TCATGTTATAAATAAAAGAAATCTTTCAGTGTTGCATTTAATAGGCATTGTGGAACATGCCTGCTGTCAG
CATTTGGGAGGTAGAGGCAGGAGGGTCAGGCATTCAAGGTCTTCCACAGCTTCATAACAAGTTCAAGATT
AGCCTAAGCTTCATGAAAACTCATCTTAAAAGCATAAAACAATGTGCATGGAATTTTCAAAGAAAAACTA
AAATAAAAATAAGAAACTAAGTGTTCTGAACACCATCACCAGCATTAGAAGTTCTATCTCTGCTGAATGT
TAATTACTCTAAATATTATATGCCATACAGAATAAGCACCCACAAAACACACTCAAAGCAAAGTGTGTAT
TTCTCTCCCATGATCATAGTCAAATCTTTTCTTAAGAGGTTTCAAACTAACCTTATTCTAAGAGATCTAT
GTCCTGAATTTTGTTTGATAATATTCCATATACCAGTTTCAGTGGTTGAATTATTACCCCATTCAGCATT
ATTTATCAATATCTGTCAAAAGACAGGGAGGTCAGGGTCATAGAAAGGGTCAGAGTCACAACCTCTGATC
TGGGGAGAGCACTGTAATGGAGATAATAAGGCCTGGATTTTGCTTCCAGGGTCTCCCCTGGGTTTTCTGG
GCTGTCAGCTCATCTGTCAGAGCCAGGGATTCCCAATTGCTATGGTGGAATTAATGGCTGCATCTTAAGC
TATATTATAATCCTTAGCAGAAGCAGACAACACAGTACTGAGAATCGCCAGATGAATGATACCTTTAAAA
CTCCTAAAACAAGCTTCGGTCAACTGATCTTTTGCAATGACTCTTCTTTTAGGATATAACGTTAAACAAA
GAAGAGAAAAAAGAAAACAGCTTTGAAATGCAAAGAGGTAGGTTGCTATTACCAATTTTGTTAAATGCTT
TAAGAGTGAAAAGAAGCTTTGGATTGGGCACATGAAACAGGGAATGCTTAGCCCTGCAAATAAAATGCAA
GACATTTGTTAAACTGCTACCTTCTCAGGCCTCTGTGATACAGAAAGGCCATGTGGATGAGGATATGTTC
CTGTTAATATTGATGATAGTAAATATGAAAAACAAAACACATCCAATACCTTTATCCAAAGGACCACACA
ATTGGCTCCATCTTCAGAGGACCAAGTGAAACAAAAGTCATCGTTTGGTAAAATTGGCATTCATCTTTCA
ATGATAACTATTTTGTGGGAGGACAGTAACCCAGTGGGTCTTCTGGGATCAATGAATACAGAGTGGCTAC
ATTCTAATCTTTGTCTGTTCTTAACATGAGAGCATCCTGGACATCTGGAGGTCATGAAAGGACCTTGATG
GCTCTCAATTCCAGGACAGCCCTGAGAATATCAATGAAGAAATTACTGAACTTATGGCCTCTGCTTAGAT
ATGCCTTGAGATAAGATACCTTATACTCAATAACACATTCCAGTCTATCTTTGAATAGCTCTAATAATTA
TATTAAGGTCAATATCTACTCAAAAAAAGGTCTTACCTCCTAACTGTGTTCCTCAGAAATTTCCTGGAGT
ATCTAATTTTGGGGCACATTTCTGTTCTTTGGAGATGTACTGAGCAAAGAATAATTACTTCTCTATATAG
CAGCGGTCTCAACACTGGAGACAGCAGCCATGGTCCCAAGTTTCCATTGAACACATACTTATTTAGGCTA
AACACACCCAGCACCTTCTACTTTATGTTCCCTTTATGATCCTTTGTAATATACCTACACAGTTTGCAGC
AGCAGGCACATAACTGGAAAGAAAGTAACCACAGTTTCTACATTAGGAGATGGGCACTTTTAATTTGGAA
GCAAGGCTCTTGCATAAGAAACAGAGCTAGATTTGAAAGTCTGGACACCTTCTTAGAATTGGGAACAAAA
CACCCAAAGAAGGAGTTACAGAGACAAAGTTTGGAGCTGAGACAAAAGGATGGACCATCTAGAGACTGCC
ATATCCAGGGATCCATTCCATAATCAGCCTCCTAACGCTGACATCATTGCATACACTAGCAAGATTTTGC
TGTAAGGACCCTGATATAGCTGTCTCTTGTGAGACTATGCCGGAGCCTAGCAAACACAGAAGTGGATGCT
CACAGTCAGCTATTGGATGGATCACAGGGCCCCCAATGGAGGAGCTAGAGAAAGGACCCAAGGAGCTGAA
GGGGTCTGCAACCCTATAGGTGGAACAACAATATGAACTAACCAGTACCCCGGAGTTCTTGACTCTAGCT
GCATATGTATCAGAAGATGGCCTAGTCGGCCATCAGTGGAATGAGAGGCCCATTGGTCGTGCAAACTTTA
TATGCCCCAGTACAGGGGAACGCCAGGGCCAAAAAGTGGGAGTGGGTGGGTAGGGGAGTGGGGGGAGGGT
ATGGGGGACTTTTGGGATAGCATTGGAAATGTAAATGAGGAAAATACAAAAAAAAAGAAAGTCTGGACAG
TCACTTGACCCAAACAGATACCATGATCATATCACTAACTCAGTTTGCAGGTACAGTGTTGTCCACTACC
ACACCAGTATATGGAATCTGTTCTTAAAAGCAAGATTCAAGGCAGCTTTAATGAAGACCAATATTTTAGT
CTGTGTCTATTTATGTTAAGTGGAATGGAGTATTGAATACCAATCAGGAAAAAGACCAATTCAGTTTTTG
AAGTACTAGAAACCACCTTTTCCTTCAGTAGGAAGGATTCCAGACCAGTTATCCTTCCTTTAACATAAAC
TACTTTAGCATAGTCACTATTATGCAGTTATAGAACTGAACCCTTTAATCTCATGAGCTGTTGTATATTT
CTTTGGCCTGACAGTTTGCTTTTGGTTTCACTCCAGGTGATGAGGATCCTCAAATTGCAGCACACGTTGT
AAGCGAAGCCAACAGTAATGCAGCATCCGGTAAGTCCCATCACTTCGGAGTGAAAGCTACCCAAGTGTAT
GAGCATGTGTGTATGTGTATGTTGGGTACTCCAAAGCCATTCGGCCTAATCATTAGGCACTTTTCTTCCT
CCAGGGACCAATTTACCAACCTACCCATATAACTCTTCATACACTGTCCTTTGTTATCAGAGTCAGCTCA
AACGCACAGATGGGACTTAGGGGGACAAAAGGAGGTGGAAACAGTCTCTATGTTCTCATTATGCTTTTTC
TCAGTGGCTGCTTCTAAATGATGAATGACTAGGTGGAGGAACCATTATTTTGCAAGTATAAAAAGAGATG
GCAGGTAGTGACCTCCTCGCTGGGAACATCTCTTCTTCTGAAACCTCTCCACTGTGTATAAATGGGCCTC
AGGAGGTCTTTTCTGTCATCTGTCAATCCCTGTATGATTAACCCCAGGCTCAGTGGGGCTGACCTCGGGG
AAATTAAAGGTAAAAATCATTTTGTAAAGATCAATAGGCGCTGAGACGTTAGATTTTTCAATGAAGTAAC
AACAGATGGCATACTGTGGTCTTTTCAACACCAATGCTTTTATTTCTATATGTATTCTACCATCATCCAG
CCCTTATTTTTTCCCCAAATCTCTACCCTGTAATAGCTAGTACTATAAAATGAATCCCCTCTCTAGATGA
ATGGAAATGTGTATGTATGCTAGCATAAAATTTCCCATATACATAAAGGCATGAGCATGGGATCAGCCCT
AGAAAGCTTCAGCAGAGTAGTTTACAATGGAGTTCTAAATCATGTGTGTGCATTTGTGCATGTGCACATG
CACACACGAGAGAGAGAGAGAAAGAGAGAGAGAGACAGACAGACAGACAGACAGACAGAGAGACAGAGAG
ACAGAGAAAGACACAGAGACACAAAAGAAGACACTGATACTGGGTTGGGTTGTTTTTGAGGTGACATGAG
CTCCTTGGTGACTATAACACAGAAGCACATGCATGATATTGTGGCTCATGGTATATAAGTAAGAGTACTG
GTTAGGGAGTTTGTGAGCACAGGGGTTTAAAAGCTAAGAATTTCTTGCTAAATGACGTTAGGCAAATCCA
ATTTATCCTGTGGCAGTTTTCTTTCTCATCTACTTTATAGAGTAGTTTTGAATATCAAATCAACTAACTA
GTGTGGAAGAAGGTTATATTATTAAGCAATATTATACACGAACAACATGCCAGGACTTAGATTCCTTCAT
TGTGATAACCAGAGATTGACCTAACATTCTTCATGGATTCCAGTTGCTCTTTTATTATTTATTGCTTTTG
TCATATACTGTTCTCTCAAAATTATGTTTATGGGAAAACACCACAATATTGCTGTGACAGAGAAACCATT
TACATATTATAGCAACAAAGAAACCTCCTAGAATCATCTCCTATAGGTCTTTATCCACCTGTACCCAAAT
CTTTTGGTCCTTGGATATATTTAATAGAATTTTGAATTTTTCAAAAGGCATAGAACTGGTACTGCCTGCC
TGTGAAATATGTCACAGTCTATATCACAGTAGATCTGTATAGGACAACATAGGGAAGATAGTACAGTACA
CTGCCACCCCAAATTTCTTATTCCTTTCTGGACATGATGCTACAAACTTGACCTAAATCCCCTAGTAATA
ACCAAAATGAAATAAGGAATTAACCAAGTGGCACATGATCTCAGTGCTAGGGAAGAAGCAAAAATATTAT
ATGTTTAAGGTCATCCAAAAGTACAAAGTGAATTCCAGGTCAACCTGGGTTCCATAAAATCTTGTCTTCC
CCCAAAAGGGGATAAATTCAGTAGACAGAGGCAGGTAGATCTCTGTGAGTCCCAAGCTAGCCTAGTCTGC
ATAACAAGTTGTAGGCCAGCTTCTGTTTTCTTTTCTGTCTCAAAAAAGAAAGCAGAAGTGTAAGTGGGTA
ATGTATTTATTAAACTGAAAAGAATCTGGTCCTTTTTTTCTCATTCAAATGGTTCAAAAGTGAAAACATC
ACAAAACAAACATCCTTTATAGAGAATTTGGGGTGCAATGTATCAGGTGCAATGCCTTCCTGTGCAAAAA
GAGGAGCCTTAATCAGTAGTATCTTATGCCATAACACATGTAAGACCATCAAATAAAACAATTAAATACC
TCAAGAAAGCAAATATATCAATACTTTTACTTCCCCCTGCCTCCCACCTTTCACCCCCATCAAATCTAGC
TGTGGAAGCTGAGATTTGAAATCGGGTGCACACACCACTTTGAACCCACTCAACAACTTGGCAGAGAAAA
GGGCACACTGTTGGTGGGGACTCTGCCCTAGCCGCAAGAATATGGGTACTTTCAAGTTGGTGGCACCCAC
TACAATGGGAGATCAAAACACAGTTAAATGAACACATGGTTTATTTTCATACTTCCCTGCCTATTTTAGG
CTTGGTCGTGGGAGGCAGGTCAGGTTTGCAACAGCATGAGGTAGAAGGAAGAAGTGGGGTCTTGACTCTG
AGCTGACGCTAATCTAGGTAAACTGACAACTCTAGCTATGTAACATTCATGATAAGTTAAATGTTTGCAC
TCCTGTTTAGCAAGAATTTTATAACATTCATAAATCTCAAGTCATTTATGCTTCATTTTAAAACCATGTA
TTTATTTATGTTTGAGTATGCCTGTCTGTGTGAATGTATGTACACATATAAGAAGGGTAGTGGAGGTACA
CAAAGATCAGATGACGGTGTCCTTGTCTTAGCACTCTCCACCTAGTCTCCTGGACTAGGAGCTTTCCTTG
AACCTGGGACTCAAGTCTTCTCATGTAGGTTGGGTACCAGCGTGTCTCAGTGATCTCCTCTATGCCTGAC
CACCCCAGTCCCTTTTGTGTTGTTGTTGTTTTGAAACAGGGTCTTGCTTAGCCCTGATAGGTCTCAAAGT
CAGTATGTGGCCAAGGATGACGTTGACCTTGCCTTCATGATTCTCCTGCTTCAATGTTGTCTGGGAATTT
TAGGTGCATATCACCAAGCCTGGCTAATCATTTGCACTTTCTTAAATTCAATGGTAAATTGGTTTGGAGA
ACTCGAAAGGGAGGAGAAATTTTGCTGTTACATGCCATTTTATTTAACCTTTTCAGATCTCTGAAACATG
CTGTAATACTGTCCCTGTTCTGTTGATTCAGAGTTAGTGTCAGGTTCCAATCTGGGGAGATCACGTGATG
TGCCCAAGTTTGAAGAAAACCAAGGGGGAAAAAAAAAAACAAACCTCTGAAGCCCATATAAACTTGGTCT
CTGTAATCCCTTGTGCCTCTGAGGGCCATAAAGTGCGTTGAGAATTCATTCTCACATGAAGTCGGCATCT
GACCTTAAACCTTATTTCCTGTTAGAATATATGCCGTGCTGTGCTTAAACTGACCAGCGATTCCCTCTCT
TTCTTACAGTTCTACAGTGGGCCAAGAAAGGATATTATACCATGAAAAGCAACTTGGTAATGCTTGAAAA
TGGGAAACAGCTGACGGTTAAAAGAGAAGGACTCTATTATGTCTACACTCAAGTCACCTTCTGCTCTAAT
CGGGAGCCTTCGAGTCAACGCCCATTCATCGTCGGCCTCTGGCTGAAGCCCAGCAGTGGATCTGAGAGAA
TCTTACTCAAGGCGGCAAATACCCACAGTTCCTCCCAGCTTTGCGAGCAGCAGTCTGTTCACTTGGGCGG
AGTGTTTGAATTACAAGCTGGTGCTTCTGTGTTTGTCAACGTGACTGAAGCAAGCCAAGTGATCCACAGA
GTTGGCTTCTCATCTTTTGGCTTACTCAAACTCTGAACAGTGCGCTGTCCTAGGCTGCAGCAGGGCTGAT
GCTGGCAGTCTTCCCTATACAGCAAGTCAGTTAGGACCTGCCCTGTGTTGAACTGCCTATTTATAACCCT
AGGATCCTCCTCATGGAGAACTATTTATTATGTACCCCCAAGGCACATAGAGCTGGAATAAGAGAATTAC
AGGGCAGGCAAAAATCCCAAGGGACCCTGCTCCCTAAGAACTTACAATCTGAAACAGCAACCCCACTGAT
TCAGACAACCAGAAAAGACAAAGCCATAATACACAGATGACAGAGCTCTGATGAAACAACAGATAACTAA
TGAGCACAGTTTTGTTGTTTTATGGGTGTGTCGTTCAATGGACAGTGTACTTGACTTACCAGGGAAGATG
CAGAAGGGCAACTGTGAGCCTCAGCTCACAATCTGTTATGGTTGACCTGGGCTCCCTGCGGCCCTAGTAG

Protein Information

Protein Name

CD40 ligand

NCBI Protein GI

15011846

Protein Accession

NP_035746

Protein pI

8.31

Protein Weight

27087.92

Protein Length

260

Protein Note

Also known as IGM; IMD3; Ly62; TRAP; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; Tnfsf5

Protein Sequence

>NP_035746.2 CD40 ligand [Mus musculus]
MIETYSQPSPRSVATGLPASMKIFMYLLTVFLITQMIGSVLFAVYLHRRLDKVEEEVNLHEDFVFIKKLK
RCNKGEGSLSLLNCEEMRRQFEDLVKDITLNKEEKKENSFEMQRGDEDPQIAAHVVSEANSNAASVLQWA
KKGYYTMKSNLVMLENGKQLTVKREGLYYVYTQVTFCSNREPSSQRPFIVGLWLKPSSGSERILLKAANT
HSSSQLCEQQSVHLGGVFELQAGASVFVNVTEASQVIHRVGFSSFGLLKL

Epitope Information

IEDB Linear Epitope