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IalB

General Information
Protegen ID 254
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
VO ID VO_0010967
Taxonomy ID 224914
Molecule Role Protective antigen
Molecule Role Annotation Brucella IalB is a protective antigen (Commander et al., 2007).
COG COG5342R, under R: General function prediction only
Related Vaccines(s) B. melitensis DNA vaccine p-ialB
References
Commander et al., 2007: Commander NJ, Spencer SA, Wren BW, MacMillan AP. The identification of two protective DNA vaccines from a panel of five plasmid constructs encoding Brucella melitensis 16M genes. Vaccine. 2007; 25(1); 43-54. [PubMed: 17049676].
Gene Information
Gene Name IalB
NCBI Gene ID 1197295
Genbank Accession AE008917
Chromosome No I
Locus Tag BMEI1584
Gene Starting Position 1632893
Gene Ending Position 1633414
DNA Sequence 
>NC_003317.1:1632893-1633414 Brucella melitensis bv. 1 str. 16M chromosome I, complete sequence
TATGAAAAATTATCGTGCAATCGGTCTTGCATTCACGTTCACTGCCCTTTCCAGTCTTTCGGCCTTTGCA
GCCTCCCTGCCCGGCGGAGCAAGCACCTTGCAGGAAACCTATCAGGACTGGACCGTGTCTTGCCAGTCGC
AGAAGGATACAACAGCCTGCGTGATGCGTCAGGAGCAAAGCAGCGCCCAGGCCGGCCAGCGCGTTCTGAC
TGCCGAGCTGCGCAACGTCGCCGGCGGCAAAGTTGACGGTGTGTTGCTGATGCCGTTCGGTCTTGATCTT
GCCAAGGGCGCCTCGCTCAAGATTGATGACACCGCTGGGCCAAACCTCACCTTCTCCACCTGCCTGCCGC
AGGGCTGCCTCGCGCCAGTGAGCTTCGATGCCAAGCAGGTTGCTGCGCTGAAATCCGGCACCAACATCAA
TGTCACCACGACGGCGCTCAGCCCGAGCCAGCCGGTTGCCTTCAAGATTTCCCTGAAAGGCTTCGGTGCC
GCGCTCGACCGCATTCAGGCATTGACCAAGTA
Protein Information
Protein Name invasion protein B
NCBI Protein GI 17987867
Protein Accession NP_540501
Protein pI 8.98
Protein Weight 17016.04
Protein Length 173
Protein Sequence 
>NP_540501.1 invasion protein B [Brucella melitensis bv. 1 str. 16M]
MKNYRAIGLAFTFTALSSLSAFAASLPGGASTLQETYQDWTVSCQSQKDTTACVMRQEQSSAQAGQRVLT
AELRNVAGGKVDGVLLMPFGLDLAKGASLKIDDTAGPNLTFSTCLPQGCLAPVSFDAKQVAALKSGTNIN
VTTTALSPSQPVAFKISLKGFGAALDRIQALTK
Vaxign Prediction
Localization(Probability) Unknown
(Prob.=0.25)
Adhesin Probability 0.776
Trans-membrane Helices 1
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope