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Bp26

General Information
Protegen ID 232
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
VO ID VO_0010962
Taxonomy ID 224914
Molecule Role Protective antigen
Molecule Role Annotation This is a protective antigen (Yang et al., 2007).
COG COG2968S, under S: Function unknown
References
Yang et al., 2007: Yang X, Walters N, Robison A, Trunkle T, Pascual DW. Nasal immunization with recombinant Brucella melitensis bp26 and trigger factor with cholera toxin reduces B. melitensis colonization. Vaccine. 2007; 25(12); 2261-2268. [PubMed: 17239499].
Gene Information
Gene Name Bp26
NCBI Gene ID 1196247
Genbank Accession AE008917
Chromosome No I
Locus Tag BMEI0536
Gene Starting Position 557728
Gene Ending Position 558480
DNA Sequence 
>NC_003317.1:557728-558480 Brucella melitensis bv. 1 str. 16M chromosome I, complete sequence
TTTACTTGATTTCAAAAACGACATTGACCGATACGTTATAGCTGTTTTCGCCTGCGGCAATCGGCACGGA
ATTGTCCGGTGCGGCTGCTAGCATGGTTCTGAACTGTCCGCGCGCAATTGGCATCGGCATGGGCGGGCGG
CTCAGTTCACTGATTTCCACCACACGGCCAAGCCCCACGCCTGCAGCGTCGGCAAGCGTCTTCGCCTTGG
CAATGGCATTGGCCACTGCGCGCTTGCGCGCCTCGTTGATCACGGCGGAGGGATTATCATTGACCAGGTT
CAAATCACCGCCCTGATTAACACCGAGCGTGACGGATTCATCCAAAATTTTTCCAACATTGGCCAGTTCG
CGCACGCGAACCGTGAGACTGGTGGATACAGAATAGCCGGTGATGGTAGGCTCTTTCAGGTTGTTCTTGT
CGTCAGGATAGACATAAATCGGCTGGATATTGATGCCGCCTGTCTGGAGATCGCGATCTTCGATGCCGGC
CTTCTTCATGGCATCGAGCACTTTTGTCATGGCTTCATTATTCGCGGTCATGGCTTCGCGCGCGGTCTTT
GCCTGGCGTAGCACCGAGAGATTGAGAATGGCCATATCGGGCGAGGCCGTCATCATGCCTTCCCCGGTGA
CGGCGATGCGCGCGGGCTGCGTCGTCATCTGATTCTCCTGTGCGAAAGCGGGCAGGCTGAAAGCGCCGAC
GAGCATGATTGTGGAAAATGAGGCTGCGAGAAAATTGCTAGCACGAGTGTTCA
Protein Information
Protein Name immunogenic protein
NCBI Protein GI 17986819
Protein Accession NP_539453
Protein pI 6.97
Protein Weight 24369.69
Protein Length 250
Protein Sequence 
>NP_539453.1 immunogenic protein [Brucella melitensis bv. 1 str. 16M]
MNTRASNFLAASFSTIMLVGAFSLPAFAQENQMTTQPARIAVTGEGMMTASPDMAILNLSVLRQAKTARE
AMTANNEAMTKVLDAMKKAGIEDRDLQTGGINIQPIYVYPDDKNNLKEPTITGYSVSTSLTVRVRELANV
GKILDESVTLGVNQGGDLNLVNDNPSAVINEARKRAVANAIAKAKTLADAAGVGLGRVVEISELSRPPMP
MPIARGQFRTMLAAAPDNSVPIAAGENSYNVSVNVVFEIK
Vaxign Prediction
Localization(Probability) Periplasmic
(Prob.=1)
Adhesin Probability 0.491
Trans-membrane Helices 1
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope