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Vaccine Comparison

WEEV DNA Vaccine encoding 6K-E1 Protein
Vaccine Information
  • Vaccine Ontology ID: VO_0011505
  • Type: DNA vaccine
  • Status: Research
  • E1 gene engineering:
    • Type: DNA vaccine construction
    • Detailed Gene Information: Click Here.
  • 6K gene engineering:
    • Type: DNA vaccine construction
    • Detailed Gene Information: Click Here.
  • Vector: pVAX (Gauci et al., 2010)
  • Immunization Route: Gene Gun
References
Gauci et al., 2010: Gauci PJ, Wu JQ, Rayner GA, Barabé ND, Nagata LP, Proll DF. Identification of Western equine encephalitis virus structural proteins that confer protection after DNA vaccination. Clinical and vaccine immunology : CVI. 2010; 17(1); 176-179. [PubMed: 19923571].
WEEV Subunit E2 Protein Vaccine
Vaccine Information
  • Vaccine Ontology ID: VO_0011506
  • Type: Subunit vaccine
  • Status: Research
  • E2 gene engineering:
    • Type: Recombinant protein preparation
    • Detailed Gene Information: Click Here.
  • Adjuvant: Titermax Gold vaccine adjuvant
  • Immunization Route: Intraperitoneal injection (i.p.)
References
 
Western equine encephalomyelitis virus PE2/E1 mutant vaccine
Vaccine Information
  • Product Name: WE2130
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Chicken
  • PE2 gene engineering:
    • Type: Gene mutation
    • Description: This PE2/E1 mutant is from Western equine encephalomyelitis virus (Turell et al., 2003).
    • Detailed Gene Information: Click Here.
  • E1 gene engineering:
    • Type: Gene mutation
    • Description: This PE2/E1 mutant is from Western equine encephalomyelitis virus (Turell et al., 2003).
    • Detailed Gene Information: Click Here.
  • Immunization Route: subcutaneous injection
References
Turell et al., 2003: Turell MJ, O'Guinn ML, Parker MD. Limited potential for mosquito transmission of genetically engineered, live-attenuated western equine encephalitis virus vaccine candidates. The American journal of tropical medicine and hygiene. 2003; 68(2); 218-221. [PubMed: 12641414].
Western equine encephalomyelitis virus PE2/E2 mutant virus
Vaccine Information
  • Product Name: WE2102
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Chicken
  • PE2 gene engineering:
    • Type: Gene mutation
    • Description: This PE2/E2 mutant is from Western equine encephalomyelitis virus (Turell et al., 2003).
    • Detailed Gene Information: Click Here.
  • E2 gene engineering:
    • Type: Gene mutation
    • Description: This PE2/E2 mutant is from Western equine encephalomyelitis virus (Turell et al., 2003).
    • Detailed Gene Information: Click Here.
  • Immunization Route: subcutaneous injection
References
Turell et al., 2003: Turell MJ, O'Guinn ML, Parker MD. Limited potential for mosquito transmission of genetically engineered, live-attenuated western equine encephalitis virus vaccine candidates. The American journal of tropical medicine and hygiene. 2003; 68(2); 218-221. [PubMed: 12641414].