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Vaccine Detail
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LM1-2-E7 |
| Vaccine Information |
- Vaccine Ontology ID: VO_0004803
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- E7 Type 16
gene engineering:
- Type: Recombinant vector construction
- Description: The E7 gene is inserted into the vector of Listeria monocytogenes, strain LM1-2 (Jia et al., 2012).
- Detailed Gene Information: Click Here.
- Vector: L. monocytogenes LM1-2 vaccine vector
- Preparation: The E7 fragment was amplified with PCR then cloned into the chromosome of L. monocytogenes (Jia et al., 2012).
- Immunization Route: Intramuscular injection (i.m.)
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| References |
Jia et al., 2012: Jia Y, Yin Y, Duan F, Fu H, Hu M, Gao Y, Pan Z, Jiao X. Prophylactic and therapeutic efficacy of an attenuated Listeria monocytogenes-based vaccine delivering HPV16 E7 in a mouse model. International journal of molecular medicine. 2012; 30(6); 1335-1342. [PubMed: 23027427].
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